Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Objective To compare the efficacy and discontinuation of augmentation agents in adult
patients with treatment-resistant depression (TRD). We conducted a systematic review and …

Interventions to improve return to work in depressed people - Nieuwenhuijsen, K - 2020 |
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Over a third of patients with major depressive disorder (MDD) do not have an adequate
response to first-line antidepressant treatments, ie, they have treatment-resistant depression …

Importance Less than one-third of patients with major depressive disorder (MDD) achieve
remission with their first antidepressant. Objective To determine the relative effectiveness …

Background Although antidepressants are often a first‐line treatment for adults with
moderate to severe depression, many people do not respond adequately to medication, and …

(1) Background: Major depressive disorder (MDD) is one of the most prevalent psychiatric
disorders worldwide. Although several antidepressant drugs have been developed, up to …

This evidence-based peer-reviewed eReport was prepared by Healthcare Global Village,
Inc. Financial support for preparation and dissemination of this eReport was provided by …

Fatigue is a frequently reported symptom in major depressive disorder, occurring in over
90% of patients. Clinical presentations of fatigue within major depressive disorder …

Treating to target in chronic diseases [eg Major Depressive Disorder (MDD)] fosters
precision, consistency, and appropriateness of treatment selection and sequencing …