Application of MIDD to accelerate the development of anti-infectives: Current status and future perspectives
This review examines the role of model-informed drug development (MIDD) in advancing
antibacterial and antiviral drug development, with an emphasis on the inclusion of host …
antibacterial and antiviral drug development, with an emphasis on the inclusion of host …
[HTML][HTML] The dark side of drug repurposing. From clinical trial challenges to antimicrobial resistance: analysis based on three major fields
Drug repurposing is a strategic endeavor that entails the identification of novel therapeutic
applications for pharmaceuticals that are already available in the market. Despite the …
applications for pharmaceuticals that are already available in the market. Despite the …
A novel humanized mouse model for HIV and tuberculosis co-infection studies
JA Bohórquez, S Adduri, D Ansari, S John… - Frontiers in …, 2024 - frontiersin.org
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to
be a major public health problem worldwide. The human immunodeficiency virus (HIV) is …
be a major public health problem worldwide. The human immunodeficiency virus (HIV) is …
Zophobas morio larvae as a novel model for the study of Acinetobacter virulence and antimicrobial resistance
N Rakovitsky, E Temkin, A Hameir… - Frontiers in …, 2024 - frontiersin.org
The use of mammalian models for in vivo testing of bacterial virulence raises ethical
concerns and is expensive and time-consuming. As an alternative, non-mammalian models …
concerns and is expensive and time-consuming. As an alternative, non-mammalian models …
Rapid Development of Animal Models for Infectious Disease Research through Vectorized Receptor Molecule Expression
The emergence and re-emergence of pathogens with pandemic potential has been a
persistent issue throughout history. Recent decades have seen significant outbreaks of …
persistent issue throughout history. Recent decades have seen significant outbreaks of …
Animal models of neglected parasitic diseases: In vivo multimodal imaging of experimental trypanosomatid infections
JMN Tsagmo, B Rotureau… - Methods in cell …, 2024 - pubmed.ncbi.nlm.nih.gov
African trypanosomiases and leishmaniases are significant neglected tropical diseases
(NTDs) that affect millions globally, with severe health and socio-economic consequences …
(NTDs) that affect millions globally, with severe health and socio-economic consequences …
[PDF][PDF] Hayvan Deneyi Modeli Kavramı ve Spesifik Deney Modelleri ile Deney Tasarımı
A Aksoy, ZN ÖZTÜRK - Turkiye Klinikleri Veterinary Sciences …, 2024 - researchgate.net
Hayvan hastalık modelleri, biyomedikal araştırmaların çeşitli aşamalarında in vivo model
olarak kullanılırlar. Bu modeller, insanlardaki hastalıkların patofizyolojisini ve hastalıklara …
olarak kullanılırlar. Bu modeller, insanlardaki hastalıkların patofizyolojisini ve hastalıklara …