Review on the pharmacological properties of lemongrass (Cymbopogon citratus) as a promising source of bioactive compounds

A Tazi, A Zinedine, JM Rocha, F Errachidi - … Research-Natural Products, 2024 - Elsevier
Despite the quantities and diversity of chemical compounds such as flavonoids discovered
in lemongrass (Cymbopogon citratus DC.), available data are fragmentary. Their variation …

Phenethyl isothiocyanate protects against cyclophosphamide-induced nephrotoxicity via nuclear factor E2–related factor 2 pathway in rats

AB Uyumlu, B Satılmış, B Atıcı… - … Biology and Medicine, 2023 - journals.sagepub.com
Phenethyl isothiocyanate (PEITC), a secondary metabolite in Cruciferous plants, exerts
chemopreventive and antioxidant effects. However, its therapeutic potential in …

[PDF][PDF] Mechanisms of cisplatin-induced acute kidney injury: pathological mechanisms, pharmacological interventions, and genetic mitigations. Cancers 2021; 13 …

KR McSweeney, LK Gadanec, T Qaradakhi, BA Ali… - 2021 - academia.edu
Administration of the chemotherapeutic agent cisplatin leads to acute kidney injury (AKI).
Cisplatin-induced AKI (CIAKI) has a complex pathophysiological map, which has been …

Anti-oxidative stress and cognitive improvement of a semi-synthetic isoorientin-based GSK-3β inhibitor in rat pheochromocytoma cell PC12 and scopolamine-induced …

Y Zhao, C He, S Hu, H Ni, X Tan, Y Zhi, L Yi, R Na… - Experimental …, 2024 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by
progressive cognitive deficits. Although the pathogenesis of AD is unclear, oxidative stress …

Antioxidant and Anti-Inflammatory Effects of 3-Dehydroxyceanothetric Acid 2-Methyl Ester Isolated from Ziziphus jujuba Mill. against Cisplatin-Induced Kidney …

D Lee, KB Kang, GS Hwang, YK Choi, TK Kim… - Biomolecules, 2021 - mdpi.com
Cisplatin is a platinum-based chemotherapeutic agent for treating solid tumors; however, it
presents a risk factor for nephropathy. In the present study, we investigated the antioxidant …

Apoptosis induction and inhibition of invasion and migration in gastric cancer cells by Isoorientin studied using network pharmacology

D Song, M Chen, X Chen, J Xu, S Wu, Y Lyu… - … Medicine and Therapies, 2024 - Springer
Background To investigate the effects of Isoorientin on the apoptosis, proliferation, invasion,
and migration of human gastric cancer cells (HGC27 cells). Methods We used network …

[PDF][PDF] Promising therapeutic efficacy of Trigonella-foenum graecum and bone marrow-derived mesenchymal stem cells on skeletal muscle atrophy in experimental rat …

HE Abd El Aty, AM Zaazaa… - … Res Appl Chem, 2023 - biointerfaceresearch.com
Skeletal muscle plasticity is maintained by various ways to regulate cell and protein
turnover. When muscle atrophy occurs, proteolytic cascades are activated, resulting in the …

Protective role of HO‐1 against acute kidney injury caused by cutaneous exposure to arsenicals

RK Srivastava, S Muzaffar, J Khan… - Annals of the New …, 2020 - Wiley Online Library
Lewisite and many other similar arsenicals are warfare vesicants developed and
weaponized for use in World Wars I and II. These chemicals, when exposed to the skin and …

Short-term supplementation of DHA-enriched phospholipids attenuates the nephrotoxicity of cisplatin without compromising its antitumor activity in mice

HH Shi, LP Chen, CC Wang, YC Zhao, CH Xue… - Food & Function, 2021 - pubs.rsc.org
Cisplatin is one of the most effective chemotherapeutic agents used for the treatment of a
wide variety of cancers. However, cisplatin has been associated with nephrotoxicity, which …

Isoorientin Alleviates Inflammatory Bowel Disease by Inhibiting NLRP3 Inflammasome Activation through Nrf2/NQO1 Pathway.

Q Cheng, X Yu, R Zhang… - Current Topics in …, 2020 - search.ebscohost.com
Inflammatory bowel disease comprises a series of related conditions characterized by
idiopathic inflammation of the gastrointestinal tract. To develop therapeutic agents to combat …