Background—Pluripotent mesenchymal stem cells (MSCs) differentiate into a variety of cells,
including cardiomyocytes and vascular endothelial cells. However, little information is …

Objective: To increase awareness of giant cell myocarditis (GCM), its pathogenesis, and
treatment. Methods: Review of relevant publications from the English-language literature …

The expression of coxsackievirus and adenovirus receptor (CAR) was dominant in the
brains and hearts of mice until the newborn phase. There is no detailed information …

Autoimmunity after viral myocarditis is considered to be one of the causes of dilated
cardiomyopathy. Cytokines are assumed to play an important role in the pathogenesis. We …

In the present study, the mechanisms and importance of the Fc portion of immunoglobulin in
experimental giant cell myocarditis were examined. Giant cell myocarditis was induced in …

Myocarditis is a poorly understood condition and its prevalence is largely underestimated. A
significant proportion of cases may be subclinical and chronic, leading to dilated …

Nuclear factor-κB (NFκB) plays a significant role in the coordinated transactivation of
cytokine, inducible NO synthase (iNOS), and adhesion molecule genes. Although …

Objectives: This study hypothesized that bone marrow–derived mononuclear cell
(BMDMNC) therapy may improve cardiac function through preventing cell death, alleviating …

Excessive NO produced by an inducible NO synthase (iNOS) has been implicated in many
types of immune-associated disorders of the cardiovascular system, but it remains to be …

FTY720 is a new immunosuppressant agent and selectively decreases the number of
circulating lymphocytes. In this study, we compared the effects of FTY720 with those of …