Quantitative X-ray powder diffraction (XRPD) data obtained from intact, consolidated
samples affords the opportunity to analyze mixtures that simulate pharmaceutical drug …

Background Losartan potassium, a common antihypertensive drug on the market, has
multiple polymorphs, of which form I is used as a pharmaceutical crystal form. Form I can be …

The application of powder X-ray diffraction (PXRD) for the detection and quantification of low
levels of a solid-state chemical impurity, BrettPhos oxide, in an active pharmaceutical …

Polymorph screening is extremely critical in the research and development of
pharmaceuticals. In this study, an easy-to-use microfluidic device was developed for the …

Anhydrous and hydrated forms of olanzapine were obtained by crystallization using different
experimental pathways and analysed by differential scanning calorimetry and …

With as high as 60% of drugs in company pipelines exhibiting poor aqueous solubility, the
ability to successfully develop a poorly water-soluble drug has become essential. Gaining a …

Finasteride (FNT) is a drug that inhibits human enzyme type II 5α‐reductase that
metabolizes testosterone into dihydrotestosterone. There are two enantiotropic polymorphs …

The experience of designing and teaching a lecture-based course about characterization
techniques commonly used in solid state chemistry and materials science in an …

With as high as 90% of drugs in the development phase and 40% of marketed products
exhibiting poor aqueous solubility, the ability to successfully develop a poorly water-soluble …

Flupirtine maleate, a pharmaceutical compound for treating psychotic disease in clinics, has
seven polymorphs. Form A, with better crystal stability and bioavailability, has been widely …