Evaluation of chemometric algorithms in quantitative X-ray powder diffraction (XRPD) of intact multi-component consolidated samples
MD Moore, RP Cogdill, PLD Wildfong - Journal of pharmaceutical and …, 2009 - Elsevier
Quantitative X-ray powder diffraction (XRPD) data obtained from intact, consolidated
samples affords the opportunity to analyze mixtures that simulate pharmaceutical drug …
samples affords the opportunity to analyze mixtures that simulate pharmaceutical drug …
Quantification of losartan potassium polymorphs using powder X-ray diffraction
Y Lou, L Zuo - Journal of AOAC International, 2021 - academic.oup.com
Background Losartan potassium, a common antihypertensive drug on the market, has
multiple polymorphs, of which form I is used as a pharmaceutical crystal form. Form I can be …
multiple polymorphs, of which form I is used as a pharmaceutical crystal form. Form I can be …
Quantification of solid-state impurity with powder X-ray diffraction using laboratory source
M Sundaram, S Natarajan, AG Dikundwar… - Powder …, 2020 - cambridge.org
The application of powder X-ray diffraction (PXRD) for the detection and quantification of low
levels of a solid-state chemical impurity, BrettPhos oxide, in an active pharmaceutical …
levels of a solid-state chemical impurity, BrettPhos oxide, in an active pharmaceutical …
Screening and Manipulation of l-Glutamic Acid Polymorphs by Antisolvent Crystallization in an Easy-to-Use Microfluidic Device
H Shi, F Li, X Huang, T Wang, Y Bao… - Industrial & …, 2020 - ACS Publications
Polymorph screening is extremely critical in the research and development of
pharmaceuticals. In this study, an easy-to-use microfluidic device was developed for the …
pharmaceuticals. In this study, an easy-to-use microfluidic device was developed for the …
Thermal study of anhydrous and hydrated forms of olanzapine
C Cavallari, A Fini, B Santos - Pharmaceutica Analytica Acta, 2013 - cris.unibo.it
Anhydrous and hydrated forms of olanzapine were obtained by crystallization using different
experimental pathways and analysed by differential scanning calorimetry and …
experimental pathways and analysed by differential scanning calorimetry and …
Optimizing the formulation of poorly water-soluble drugs
KP O'Donnell, RO Williams III - Formulating poorly water soluble drugs, 2011 - Springer
With as high as 60% of drugs in company pipelines exhibiting poor aqueous solubility, the
ability to successfully develop a poorly water-soluble drug has become essential. Gaining a …
ability to successfully develop a poorly water-soluble drug has become essential. Gaining a …
Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
SG Antonio, CO Paiva‐Santos, VDN Bezzon - Journal of Pharmaceutical …, 2014 - Elsevier
Finasteride (FNT) is a drug that inhibits human enzyme type II 5α‐reductase that
metabolizes testosterone into dihydrotestosterone. There are two enantiotropic polymorphs …
metabolizes testosterone into dihydrotestosterone. There are two enantiotropic polymorphs …
Designing and Teaching a Course about Characterization Techniques for Solid State Materials in an Undergraduate Institution
AH Pinto - Journal of Chemical Education, 2018 - ACS Publications
The experience of designing and teaching a lecture-based course about characterization
techniques commonly used in solid state chemistry and materials science in an …
techniques commonly used in solid state chemistry and materials science in an …
Optimizing the formulation of poorly water-soluble drugs
X Ma, D Ellenberger, KP O'Donnell… - Formulating Poorly Water …, 2022 - Springer
With as high as 90% of drugs in the development phase and 40% of marketed products
exhibiting poor aqueous solubility, the ability to successfully develop a poorly water-soluble …
exhibiting poor aqueous solubility, the ability to successfully develop a poorly water-soluble …
Quantification of flupirtine maleate polymorphs using X-ray powder diffraction
YM Zhao, ZB Zheng, S Li - Chinese Chemical Letters, 2016 - Elsevier
Flupirtine maleate, a pharmaceutical compound for treating psychotic disease in clinics, has
seven polymorphs. Form A, with better crystal stability and bioavailability, has been widely …
seven polymorphs. Form A, with better crystal stability and bioavailability, has been widely …