The purpose of this study was to improve the sensitivity and accuracy of quantitative analysis
of polymorphic mixtures. Various techniques such as hand grinding and mixing (in mortar …

The purpose of this study was to develop a sensitive system for detection of crystalline drug
substances in intact pharmaceutical tablets by X-ray powder diffractometry (XRPD), using …

A dual optimization salification strategy has been established for the purpose of taking
advantages of the nutrient ferulic acid (FD) to perfect the in vivo/vitro peculiarities of the …

Functional and physicochemical properties of two novel polymers from plants were
characterized with a view of determining suitability for use in pharmaceutical dosage forms …

Spectrophotometric methods of zero order, first and second derived order had been
developed for olanzapine determination in tablets using ethanol and isopropanol as solvent …

Publisher Summary This chapter discusses many of the common analytical techniques used
to characterize pharmaceutical solids. The microscopic methods can be divided into two …

Background. The biological half life of metformin requires multiple doses which are
associated with poor patient compliance. This justifies the need for a dosage form with …

A pattern-fitting procedure using an X-ray diffraction pattern was applied to the quantitative
analysis of binary system of crystalline pharmaceuticals in tablets. Orthorhombic crystals of …

As a traditional Chinese medicine and excipient, talc is widely used in medical and
pharmaceutical fields. It may be contaminated with asbestos (including tremolite and …

Objectives: Liquisolid tablets are an innovative approach to enhance the dissolution rate
and, thereby, the bioavailability of therapeutic agents with poor aqueous solubility. Materials …