Materials and general method 5 aminoisothalic acid (H2asa) was purchased from TCI
Chemicals (India) Pvt. Ltd. High purity MnCl2. 4H2O was purchased from Sigma Aldrich Co …

Olanzapine key starting material, 5-methyl-2-((2-nitrophenyl) amino) thiophene-3-
carbonitrile (3), is a key starting material of Olanzapine. During the impurity profile study an …

An extensive experimental search for solid forms of the antipsychotic compound olanzapine
identified 60 distinct solid forms including three nonsolvated polymorphs, 56 crystalline …

The objective of this work was to introduce a novel method for predicting solid dispersion
potential enabled by the ability to differentiate phase-separated co-solidified products from …

Objective: Eplerenone (EPL) is a selective aldosterone blocker used for the treatment of
cardiovascular disease. It is known from the literature that the Polymorphs of EPL, form-H …

Ceiba pentandra (CP) is a useful native plant with desirable therapeutic properties.
However, its potentials as pharmaceutical excipient have not been extensively reported. In …

Direct derivation (DD) is a novel Powder X-ray diffraction quantification method based on
intensity–composition equation, which can determine the weight fraction of individual …

The prevalence of counterfeit and substandard medicines has been growing rapidly over the
past decade, and fast, non-destructive techniques for their detection are urgently needed to …

Spectrophotometric methods of zero order, first and second derived order had been
developed for olanzapine determination in tablets using ethanol and isopropanol as solvent …

Congestive heart failure is a type of disease which is mainly observed due to the improper
supply of blood to the heart. In this disease patient feels severe pain in the chest and may …