Microglial phagocytosis of neurons in neurodegeneration, and its regulation
CA Butler, AS Popescu, EJA Kitchener… - Journal of …, 2021 - Wiley Online Library
There is growing evidence that excessive microglial phagocytosis of neurons and synapses
contributes to multiple brain pathologies. RNA‐seq and genome‐wide association (GWAS) …
contributes to multiple brain pathologies. RNA‐seq and genome‐wide association (GWAS) …
Microglia in the retina: roles in development, maturity, and disease
SM Silverman, WT Wong - Annual review of vision science, 2018 - annualreviews.org
Microglia, the primary resident immune cell type, constitute a key population of glia in the
retina. Recent evidence indicates that microglia play significant functional roles in the retina …
retina. Recent evidence indicates that microglia play significant functional roles in the retina …
Microglia in CNS development: Shaping the brain for the future
Microglial cells are the resident macrophages of the central nervous system (CNS) and are
mainly known for their roles in neuropathologies. However, major recent developments have …
mainly known for their roles in neuropathologies. However, major recent developments have …
Microglia-neuron crosstalk: Signaling mechanism and control of synaptic transmission
S Marinelli, B Basilico, MC Marrone… - Seminars in cell & …, 2019 - Elsevier
The continuous crosstalk between microglia and neurons is required for microglia
housekeeping functions and contributes to brain homeostasis. Through these exchanges …
housekeeping functions and contributes to brain homeostasis. Through these exchanges …
Plasticity of microglia
Microglial cells are the scions of foetal macrophages which invade the neural tube early
during embryogenesis. The nervous tissue environment instigates the phenotypic …
during embryogenesis. The nervous tissue environment instigates the phenotypic …
[HTML][HTML] Microglia gone rogue: impacts on psychiatric disorders across the lifespan
TL Tay, C Béchade, I D'andrea, MK St-Pierre… - Frontiers in molecular …, 2018 - frontiersin.org
Microglia are the predominant immune response cells and professional phagocytes of the
central nervous system (CNS) that have been shown to be important for brain development …
central nervous system (CNS) that have been shown to be important for brain development …
Microglia‐dependent remodeling of neuronal circuits
JR Guedes, PA Ferreira, JM Costa… - Journal of …, 2022 - Wiley Online Library
Microglia are tissue‐resident macrophages responsible for the surveillance, neuronal
support, and immune defense of the brain parenchyma. Recently, the role played by …
support, and immune defense of the brain parenchyma. Recently, the role played by …
[HTML][HTML] Function and dysfunction of microglia during brain development: consequences for synapses and neural circuits
RC Paolicelli, MT Ferretti - Frontiers in Synaptic Neuroscience, 2017 - frontiersin.org
Many diverse factors, ranging from stress to infections, can perturb brain homeostasis and
alter the physiological activity of microglia, the immune cells of the central nervous system …
alter the physiological activity of microglia, the immune cells of the central nervous system …
[HTML][HTML] Microglia, cytokines, and neural activity: unexpected interactions in brain development and function
A Ferro, YSS Auguste, L Cheadle - Frontiers in immunology, 2021 - frontiersin.org
Intercellular signaling molecules such as cytokines and their receptors enable immune cells
to communicate with one another and their surrounding microenvironments. Emerging …
to communicate with one another and their surrounding microenvironments. Emerging …
Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo
RD Stowell, EL Wong, HN Batchelor… - Developmental …, 2018 - Wiley Online Library
Microglia are the innate immune cells of the central nervous system and are also important
participants in normal development and synaptic plasticity. Here, we demonstrate that the …
participants in normal development and synaptic plasticity. Here, we demonstrate that the …