[HTML][HTML] Targeting SREBP-1-mediated lipogenesis as potential strategies for cancer

Q Zhao, X Lin, G Wang - Frontiers in oncology, 2022 - frontiersin.org
Sterol regulatory element binding protein-1 (SREBP-1), a transcription factor with a basic
helix–loop–helix leucine zipper, has two isoforms, SREBP-1a and SREBP-1c, derived from …

[HTML][HTML] Crosstalk between metabolism and cell death in tumorigenesis

S Yang, C Hu, X Chen, Y Tang, J Li, H Yang, Y Yang… - Molecular Cancer, 2024 - Springer
It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to
such an abnormally rapid proliferation rate, cancer cells constantly encounter the limits of …

Hydroxytyrosol attenuates ethanol-induced liver injury by ameliorating steatosis, oxidative stress and hepatic inflammation by interfering STAT3/iNOS pathway

X Fang, J Cao, Z Tao, Z Yang, Y Dai, L Zhao - Redox Report, 2023 - Taylor & Francis
Objective: Hydroxytyrosol (HT) is a polyphenol with a wide range of biological activities.
Excessive drinking can lead to oxidative stress and inflammation in the liver, which usually …

[HTML][HTML] Circadian clock and lipid metabolism disorders: a potential therapeutic strategy for cancer

M Liu, Z Zhang, Y Chen, T Feng, Q Zhou… - Frontiers in …, 2023 - frontiersin.org
Recent research has emphasized the interaction between the circadian clock and lipid
metabolism, particularly in relation to tumors. This review aims to explore how the circadian …

[HTML][HTML] The role of metabolic reprogramming in cancer metastasis and potential mechanism of traditional Chinese medicine intervention

D Wang, F Wang, X Kong, Q Li, H Shi, S Zhao… - Biomedicine & …, 2022 - Elsevier
Metabolic reprogramming is one of the most prominent features underlying cancer cells
progression and metastasis. Traditional Chinese medicine (TCM) has been widely used in …

[HTML][HTML] Alpinumisoflavone exhibits the therapeutic effect on prostate cancer cells by repressing AR and co-targeting FASN-and HMGCR-mediated lipid and …

P Basavaraj, P Ruangsai, PF Hsieh, WP Jiang, DT Bau… - Life, 2022 - mdpi.com
Prostate cancer (PCa) is the most common cancer in men, and this has been mainly noticed
in Western and Asian countries. The aggregations of PCa and castration-resistant PCa …

[HTML][HTML] New insights into lipid metabolism and prostate cancer

Z Zhang, W Wang, P Kong, K Feng… - International …, 2023 - spandidos-publications.com
Prostate cancer (PCa) is the most common malignant tumor of the male urological system
and poses a severe threat to the survival of middle‑aged and elderly males worldwide. The …

[HTML][HTML] Co-morbid intersections of cancer and cardiovascular disease and targets for natural drug action: Reprogramming of lipid metabolism

G Zhu, L Cao, J Wu, M Xu, Y Zhang, M Wu… - Biomedicine & …, 2024 - Elsevier
Cancer and cardiovascular diseases are major contributors to global morbidity and mortality,
and their seemingly separate pathologies are intricately intertwined. In the context of cancer …

[HTML][HTML] Elucidation of scandenolone as anti-cancer activity through impairment of the metabolic and signaling vulnerabilities in prostate cancer

P Basavaraj, PF Hsieh, WP Jiang, DT Bau… - Biomedicine & …, 2023 - Elsevier
Prostate cancer (PCa) is the most prevalent men's cancer in America and Western countries.
No effective therapies are currently available for PCa aggressiveness, including castration …

Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis

M Jin, J Li, L Zheng, M Huang, Y Wu, Q Huang… - International …, 2024 - Elsevier
Background In this study, we investigated whether Exo regulate the proliferation and
invasion of PC. Methods In this study, we isolated the Eriobotrya japonica Exo using Ultra …