[HTML][HTML] Targeting SREBP-1-mediated lipogenesis as potential strategies for cancer
Q Zhao, X Lin, G Wang - Frontiers in oncology, 2022 - frontiersin.org
Sterol regulatory element binding protein-1 (SREBP-1), a transcription factor with a basic
helix–loop–helix leucine zipper, has two isoforms, SREBP-1a and SREBP-1c, derived from …
helix–loop–helix leucine zipper, has two isoforms, SREBP-1a and SREBP-1c, derived from …
[HTML][HTML] Crosstalk between metabolism and cell death in tumorigenesis
S Yang, C Hu, X Chen, Y Tang, J Li, H Yang, Y Yang… - Molecular Cancer, 2024 - Springer
It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to
such an abnormally rapid proliferation rate, cancer cells constantly encounter the limits of …
such an abnormally rapid proliferation rate, cancer cells constantly encounter the limits of …
Hydroxytyrosol attenuates ethanol-induced liver injury by ameliorating steatosis, oxidative stress and hepatic inflammation by interfering STAT3/iNOS pathway
X Fang, J Cao, Z Tao, Z Yang, Y Dai, L Zhao - Redox Report, 2023 - Taylor & Francis
Objective: Hydroxytyrosol (HT) is a polyphenol with a wide range of biological activities.
Excessive drinking can lead to oxidative stress and inflammation in the liver, which usually …
Excessive drinking can lead to oxidative stress and inflammation in the liver, which usually …
[HTML][HTML] Circadian clock and lipid metabolism disorders: a potential therapeutic strategy for cancer
M Liu, Z Zhang, Y Chen, T Feng, Q Zhou… - Frontiers in …, 2023 - frontiersin.org
Recent research has emphasized the interaction between the circadian clock and lipid
metabolism, particularly in relation to tumors. This review aims to explore how the circadian …
metabolism, particularly in relation to tumors. This review aims to explore how the circadian …
[HTML][HTML] The role of metabolic reprogramming in cancer metastasis and potential mechanism of traditional Chinese medicine intervention
D Wang, F Wang, X Kong, Q Li, H Shi, S Zhao… - Biomedicine & …, 2022 - Elsevier
Metabolic reprogramming is one of the most prominent features underlying cancer cells
progression and metastasis. Traditional Chinese medicine (TCM) has been widely used in …
progression and metastasis. Traditional Chinese medicine (TCM) has been widely used in …
[HTML][HTML] Alpinumisoflavone exhibits the therapeutic effect on prostate cancer cells by repressing AR and co-targeting FASN-and HMGCR-mediated lipid and …
Prostate cancer (PCa) is the most common cancer in men, and this has been mainly noticed
in Western and Asian countries. The aggregations of PCa and castration-resistant PCa …
in Western and Asian countries. The aggregations of PCa and castration-resistant PCa …
[HTML][HTML] New insights into lipid metabolism and prostate cancer
Z Zhang, W Wang, P Kong, K Feng… - International …, 2023 - spandidos-publications.com
Prostate cancer (PCa) is the most common malignant tumor of the male urological system
and poses a severe threat to the survival of middle‑aged and elderly males worldwide. The …
and poses a severe threat to the survival of middle‑aged and elderly males worldwide. The …
[HTML][HTML] Co-morbid intersections of cancer and cardiovascular disease and targets for natural drug action: Reprogramming of lipid metabolism
G Zhu, L Cao, J Wu, M Xu, Y Zhang, M Wu… - Biomedicine & …, 2024 - Elsevier
Cancer and cardiovascular diseases are major contributors to global morbidity and mortality,
and their seemingly separate pathologies are intricately intertwined. In the context of cancer …
and their seemingly separate pathologies are intricately intertwined. In the context of cancer …
[HTML][HTML] Elucidation of scandenolone as anti-cancer activity through impairment of the metabolic and signaling vulnerabilities in prostate cancer
Prostate cancer (PCa) is the most prevalent men's cancer in America and Western countries.
No effective therapies are currently available for PCa aggressiveness, including castration …
No effective therapies are currently available for PCa aggressiveness, including castration …
Corosolic acid delivered by exosomes from Eriobotrya japonica decreased pancreatic cancer cell proliferation and invasion by inducing SAT1-mediated ferroptosis
M Jin, J Li, L Zheng, M Huang, Y Wu, Q Huang… - International …, 2024 - Elsevier
Background In this study, we investigated whether Exo regulate the proliferation and
invasion of PC. Methods In this study, we isolated the Eriobotrya japonica Exo using Ultra …
invasion of PC. Methods In this study, we isolated the Eriobotrya japonica Exo using Ultra …