Metastatic outgrowth via the two-way interplay of autophagy and metabolism

AB Behrooz, M Cordani, M Donadelli… - Biochimica et Biophysica …, 2023 - Elsevier
Metastasis represents one of the most dangerous issue of cancer progression, characterized
by intricate interactions between invading tumor cells, various proteins, and other cells on …

Mitochondrial glutathione in cellular redox homeostasis and disease manifestation

TH Chen, HC Wang, CJ Chang, SY Lee - International Journal of …, 2024 - mdpi.com
Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …

Dynamics of redox signaling in aging via autophagy, inflammation, and senescence

PS Javali, M Sekar, A Kumar, K Thirumurugan - Biogerontology, 2023 - Springer
Review paper attempts to explain the dynamic aspects of redox signaling in aging through
autophagy, inflammation, and senescence. It begins with ROS source in the cell, then states …

Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats

M Demir, E Altinoz, O Koca, H Elbe, MO Onal, Y Bicer… - Tissue and Cell, 2023 - Elsevier
Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible
to prevent the side effects of DXR. The aim of this study was to investigate the …

Exploring Importance and Regulation of Autophagy in Cancer Stem Cells and Stem Cell-Based Therapies

MA Rahman, EH Apu, SM Rakib-Uz-Zaman… - Cells, 2024 - mdpi.com
Autophagy is a globally conserved cellular activity that plays a critical role in maintaining
cellular homeostasis through the breakdown and recycling of cellular constituents. In recent …

Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment

A Elmetwalli, MO Abdel-Monem, AH El-Far, GS Ghaith… - Medical Oncology, 2024 - Springer
Recent advances in nanotechnology have offered novel ways to combat cancer. By utilizing
the reducing capabilities of Lactobacillus acidophilus, silver nanoparticles (AgNPs) are …

Synergistic antimicrobial and antiproliferative proficiency of Phaseolus vulgaris seed extract-derived silver nanoparticles: a green fabrication approach

MA Mir, NP Negi, V Raja, MK Aulakh - Clean Technologies and …, 2023 - Springer
This study represents a sustainable and environmentally friendly approach to synthesizing
silver nanoparticles employing the seed extract of Phaseolus vulgaris. Spectrophotometric …

Phellinus merrillii extracts induce apoptosis of vascular smooth muscle cells via intrinsic and extrinsic pathways

PY Chou, YT Lu, MJ Sheu - Food Science & Nutrition, 2023 - Wiley Online Library
Restenosis frequently occurs after balloon angioplasty. Percutaneous coronary intervention
(PCI)‐induced artery damage is a significant part of triggering restenosis of the vascular …

Enhancing Anticancer Efficacy of Formononetin Microspheres via Microfluidic Fabrication

X Cao, Q Li, X Li, Q Liu, K Liu, T Deng, X Weng… - AAPS …, 2023 - Springer
Formononetin is a flavonoid compound with anti-tumor and anti-inflammatory properties.
However, its low solubility limits its clinical use. We employed microfluidic technology to …

PEX14 acts as the interface linking optineurin to cell type-selective pexophagy

H Li, S Chen, Z Claes, C Lismont, B Vandewinkel… - bioRxiv, 2024 - biorxiv.org
Peroxisome degradation, known as pexophagy, is essential for eliminating surplus and
dysfunctional peroxisomes, with dysregulation linked to various diseases. Previous research …