Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms

MJ Stuart, S Kelsey - US Patent 9,375,485, 2016 - Google Patents
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Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors

E Bassett, B Burington, H Wang, K Eng - US Patent 9,200,327, 2015 - Google Patents
US9200327B2 - Diagnostic markers for treating cell proliferative disorders with telomerase
inhibitors - Google Patents US9200327B2 - Diagnostic markers for treating cell proliferative …

CNS-tumor treatment method and composition

DF Deen, IIWH Frey, S Gryaznov - US Patent 8,153,604, 2012 - Google Patents
A method, aerosol composition, and aerosolizing device for treating a brain tumor in a
subject are disclosed. The method includes intranasally administering to the subject, an …

Antiproliferative activity of g-rich oligonucleotides and method of using same to bind to nucleolin

DM Miller, PJ Bates, JO Trent - US Patent 7,314,926, 2008 - Google Patents
The present invention provides a method for inhibiting the proliferation of malignant and/or
hyperplastic cells in a Subject by administering to the Subject a therapeutically effective …

TRBD-binding effectors and methods for using the same to modulate telomerase activity

E Skordalakes - US Patent 8,377,992, 2013 - Google Patents
US8377992B2 - TRBD-binding effectors and methods for using the same to modulate
telomerase activity - Google Patents US8377992B2 - TRBD-binding effectors and methods for …

Treatment of carcinomas with a combination of EGF-pathway and telomerase inhibitors

RJ Tressler, NF Go - US Patent 9,155,753, 2015 - Google Patents
A method and kit for inhibiting the proliferation of carcinoma cells are disclosed, based on a
combination of an EGF pathway inhibitor and a telomerase inhibitor. When used in cancer …

Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin

DM Miller, PJ Bates, JO Trent - US Patent 8,648,051, 2014 - Google Patents
The present invention provides a method for inhibiting the proliferation of malignant and/or
hyperplastic cells in a subject by administering to the subject a therapeutically effective …

Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin

JO Trent, PJ Bates, DJ Miller - US Patent 8,114,850, 2012 - Google Patents
Compositions and methods for modulating tumor proliferation in an individual are provided.
The methods employ nucleolin-binding agents, such as aptamers. The aptamers of the …

Methods, compositions, and kits for modulating tumor cell proliferation

C Green, D Jones - US Patent App. 11/985,827, 2009 - Google Patents
US20090131351A1 - Methods, compositions, and kits for modulating tumor cell proliferation -
Google Patents US20090131351A1 - Methods, compositions, and kits for modulating tumor …

Oligonucleotide compositions and methods of making the same

PH Ramiya - US Patent 10,392,418, 2019 - Google Patents
The present disclosure provides a solid phase method of making oligonucleotides via
sequential coupling cycles including at least one coupling of a dinucleotide dimer subunit to …