PIFE was first used as an acronym for protein-induced fluorescence enhancement, which
refers to the increase in fluorescence observed upon the interaction of a fluorophore, such …

Levels of biological thiols, or “biothiols,” in mitochondria can be used to assess
environmental and biological oxidative stress, which can cause health issues such as …

Fluorescent materials with high brightness play a crucial role in the advancement of various
technologies such as bioimaging, photonics, and OLEDs. While significant efforts are …

In vivo imaging using shortwave infrared (SWIR) light (1,000–2,000 nm) benefits from
deeper penetration and higher resolution compared with using visible and near-infrared …

Background Near-infrared cyanine dyes have high sensitivity and spatial resolution imaging
capabilities, but they also have unavoidable drawbacks such as photobleaching, low water …

Microenvironmental indicators in organisms drive the operation of different physiological
functions. In contrast, disruption of microenvironmental homeostasis is often closely …

Osteosarcoma (OS) is the most prevalent carcinoma of the skeletal system with high rate of
mortality and morbidity. The rate of limb salvage and overall survival for patients with …

Conventional cyanine dyes exist as “always-on” fluorescent probes leading to inevitable
background signals which often limit their performance and scope of applications. To …

Intracellular RNA imaging with organic small molecular probes has been an intense topic,
although the number of such reported dyes, particularly dyes with high quantum yields and …

SO2, a gas signaling molecule, can be produced endogenously in mitochondria. Its
hydrolysate, HSO3–, plays a key role in food preservation, cardiovascular relaxation, and …