Carbapenemase-producing Enterobacteriaceae (CPE) are an important and increasing
threat to global health. Both clonal spread and plasmid-mediated transmission contribute to …

The global emergence of carbapenemase-producing bacteria capable of hydrolyzing the
once effective carbapenem antibiotics is considered a contemporary public health concern …

Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now
threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae …

First variants of the Klebsiella pneumoniae carbapenemase (KPC), KPC-2 and KPC-3, have
encountered a worldwide success, particularly in K. pneumoniae isolates. These beta …

Environmental reservoirs of antibiotic resistance (AR) are a growing concern that are
gathering more attention as potential sources for human infection. Carbapenem-resistant …

Antibiotic resistance is one of the greatest public-health challenges worldwide, especially
with regard to Gram-negative bacteria (GNB). Carbapenems are the β-lactam antibiotics of …

Aquatic ecosystems harbor a vast pool of antibiotic resistance genes (ARGs), which can
suffer mutation, recombination and selection events. Here, we explored the diversity of …

Aeromonas hydrophila and Aeromonas caviae adapt to saline water environments and are
the most predominant Aeromonas species isolated from estuaries. Here, we isolated …

Carbapenemase-producing bacteria (CPB) are rare, multidrug resistant organisms most
commonly associated with hospitalized patients. Metropolitan wastewater treatment plants …

The emergence and spread of resistance to antibiotics among bacteria is the most serious
global threat to public health in recent and coming decades. In this study, we characterized …