Association between HTLV-1 infection and adverse health outcomes: a systematic review and meta-analysis of epidemiological studies

G Schierhout, S McGregor, A Gessain… - The Lancet Infectious …, 2020 - thelancet.com
Background Human T-cell lymphotropic virus type 1 (HTLV-1) is a human retrovirus that
causes a lifelong infection. Several diseases, including an aggressive form of leukaemia …

[HTML][HTML] 40 years of the human T-cell leukemia virus: past, present, and future

Y Tagaya, M Matsuoka, R Gallo - F1000Research, 2019 - ncbi.nlm.nih.gov
It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …

[HTML][HTML] Blocking HTLV-1/2 silent transmission in Brazil: current public health policies and proposal for additional strategies

C Rosadas, MLB Menezes… - PLoS Neglected …, 2021 - journals.plos.org
Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but
remain silent and neglected infections. HTLV-1 is associated with a range of diseases with …

[HTML][HTML] HTLV-1 extracellular vesicles promote cell-to-cell contact

DO Pinto, C DeMarino, ML Pleet, M Cowen… - Frontiers in …, 2019 - frontiersin.org
Human T-cell leukemia virus-1 (HTLV-1) is a neglected and incurable retrovirus estimated to
infect 5 to 10 million worldwide. Specific indigenous Australian populations report infection …

Integrated molecular and immunological features of human T-lymphotropic virus type 1 infection and disease progression to adult T-cell leukaemia or lymphoma

JS O'Donnell, SK Hunt, KJ Chappell - The Lancet Haematology, 2023 - thelancet.com
The human T-lymphotropic virus type 1 (HTLV-1) retrovirus infects 10–20 million people
globally, with endemic regions in southwestern Japan, the Caribbean basin, Africa, and …

[HTML][HTML] Precise excision of HTLV-1 provirus with a designer-recombinase

T Rojo-Romanos, J Karpinski, S Millen, N Beschorner… - Molecular Therapy, 2023 - cell.com
The human T cell leukemia virus type 1 (HTLV-1) is a pathogenic retrovirus that persists as a
provirus in the genome of infected cells and can lead to adult T cell leukemia (ATL) …

Transmission of CMV, HTLV-1, and HIV through breastmilk

AJ Prendergast, AE Goga, C Waitt… - The Lancet Child & …, 2019 - thelancet.com
Breastfeeding is a crucial child survival intervention. However, the potential for transmission
of viral infections from mother to child presents the dilemma of how best to interpret the …

[HTML][HTML] Very high prevalence of infection with the human T cell leukaemia virus type 1c in remote Australian Aboriginal communities: Results of a large cross …

L Einsiedel, H Pham, MR Talukder… - PLoS neglected …, 2021 - journals.plos.org
Infection with the human T cell leukaemia virus type 1 (HTLV-1) subtype C is endemic
among Aboriginal people in central Australia. To provide insights into the risk factors for …

An HTLV-1 envelope mRNA vaccine is immunogenic and protective in New Zealand rabbits

JJ Tu, E King, V Maksimova, S Smith, R Macias… - Journal of …, 2024 - Am Soc Microbiol
mRNA vaccine technology has proven to be a viable approach for effectively triggering
immune responses that protect against or limit viral infections and disease. In our study, we …

Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1–associated myelopathy/tropical spastic paraparesis

M Nagasaka, M Yamagishi… - Proceedings of the …, 2020 - National Acad Sciences
Human T cell leukemia virus 1 (HTLV-1) causes the functionally debilitating disease HTLV-1–
associated myelopathy/tropical spastic paraparesis (HAM/TSP) as well as adult T cell …