Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

Following primary infection, human cytomegalovirus (HCMV) establishes lifelong latency
and periodically reactivates without causing symptoms in healthy individuals. In the absence …

A cytomegalovirus (CMV) vaccine that is effective at preventing congenital infection and
reducing CMV disease in transplant patients remains a high priority as no approved …

T cell recognition of specific antigens mediates protection from pathogens and controls
neoplasias, but can also cause autoimmunity. Our knowledge of T cell antigens and their …

Human cytomegalovirus (HCMV) infections of immunocompetent hosts are characterized by
a dynamic, life-long interaction in which host immune responses, particularly of T cells …

Human cytomegalovirus (CMV) is a betaherpesvirus in the same family as human
herpesvirus-6 and-7. CMV is a large virus including approximately 200 proteins. CMV has …

After initial infection, human cytomegalovirus remains in a persistent state with the host.
Immunity against the virus controls replication, although intermitent viral shedding can still …

The finding that individual cancers contain many mutant genes not present in normal tissues
has prompted considerable interest in the cancer epitope landscape. To further understand …

Hosts with compromised or naive immune systems, such as individuals living with HIV/AIDS,
transplant recipients, and fetuses, are at the highest risk for complications from …

The age-associated decrease in functionality of the human immune system is thought to
have a negative impact on the capacity to provide protection against infection, in turn …