Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
Imaging the limbic system in Parkinson's disease—a review of limbic pathology and clinical symptoms
M Banwinkler, H Theis, S Prange, T van Eimeren - Brain sciences, 2022 - mdpi.com
The limbic system describes a complex of brain structures central for memory, learning, as
well as goal directed and emotional behavior. In addition to pathological studies, recent …
well as goal directed and emotional behavior. In addition to pathological studies, recent …
Kidney damage causally affects the brain cortical structure: a Mendelian randomization study
X Chen, J Kong, J Pan, K Huang, W Zhou, X Diao… - …, 2021 - thelancet.com
Background Alterations in the brain cortical structures of patients with chronic kidney
disease (CKD) have been reported; however, the cause has not been determined yet …
disease (CKD) have been reported; however, the cause has not been determined yet …
The default mode network and cognition in Parkinson's disease: A multimodal resting‐state network approach
MC Ruppert, A Greuel, J Freigang… - Human brain …, 2021 - Wiley Online Library
Involvement of the default mode network (DMN) in cognitive symptoms of Parkinson's
disease (PD) has been reported by resting‐state functional MRI (rsfMRI) studies. However …
disease (PD) has been reported by resting‐state functional MRI (rsfMRI) studies. However …
Morphological basis of Parkinson disease-associated cognitive impairment: an update
KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …
TGR5 agonist INT-777 alleviates inflammatory neurodegeneration in Parkinson's disease mouse model by modulating mitochondrial dynamics in microglia
R Huang, Y Gao, J Chen, Q Duan, P He, J Zhang… - Neuroscience, 2022 - Elsevier
Parkinson's disease (PD) is one of the most common chronic progressive
neurodegenerative diseases that affects both motor and non-motor functions. Bile acids …
neurodegenerative diseases that affects both motor and non-motor functions. Bile acids …
Pathobiology of cognitive impairment in Parkinson disease: challenges and outlooks
KA Jellinger - International Journal of Molecular Sciences, 2023 - mdpi.com
Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …
that poses a severe burden on the patients and caregivers, yet relatively little is known about …
Longitudinal clinical, cognitive, and neuroanatomical changes over 5 years in GBA-positive Parkinson's disease patients
M Leocadi, E Canu, G Donzuso, T Stojkovic… - Journal of …, 2022 - Springer
Objective To study the longitudinal disease course of Parkinson's disease (PD) patients with
glucocerebrosidase (GBA) mutation (GBA-positive) compared to PD non-carriers (GBA …
glucocerebrosidase (GBA) mutation (GBA-positive) compared to PD non-carriers (GBA …
[HTML][HTML] Regional changes of brain structure during progression of idiopathic Parkinson's disease–A longitudinal study using deformation based morphometry
P Pieperhoff, M Südmeyer, L Dinkelbach, CJ Hartmann… - Cortex, 2022 - Elsevier
Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder with a broad spectrum
of motor and non-motor symptoms. The neuropathological characteristics of idiopathic PD …
of motor and non-motor symptoms. The neuropathological characteristics of idiopathic PD …
A selective NLRP3 inflammasome inhibitor attenuates behavioral deficits and neuroinflammation in a mouse model of Parkinson's disease
S Huang, Z Chen, B Fan, Y Chen, L Zhou… - Journal of …, 2021 - Elsevier
Nod-like receptor pyrin containing (NLRP) 3 inflammasome-mediated neuroinflammation is
involved in the pathology of Parkinson's disease (PD), but the roles of other inflammasomes …
involved in the pathology of Parkinson's disease (PD), but the roles of other inflammasomes …