[HTML][HTML] Biological response of cancer cells to radiation treatment

R Baskar, J Dai, N Wenlong, R Yeo… - Frontiers in molecular …, 2014 - frontiersin.org
Cancer is a class of diseases characterized by uncontrolled cell growth and has the ability to
spread or metastasize throughout the body. In recent years, remarkable progress has been …

[HTML][HTML] Cellular pathways in response to ionizing radiation and their targetability for tumor radiosensitization

P Maier, L Hartmann, F Wenz, C Herskind - International journal of …, 2016 - mdpi.com
During the last few decades, improvements in the planning and application of radiotherapy
in combination with surgery and chemotherapy resulted in increased survival rates of tumor …

Strategies to improve radiotherapy with targeted drugs

AC Begg, FA Stewart, C Vens - Nature Reviews Cancer, 2011 - nature.com
Radiotherapy is used to treat approximately 50% of all cancer patients, with varying success.
The dose of ionizing radiation that can be given to the tumour is determined by the sensitivity …

Strategies for optimizing the response of cancer and normal tissues to radiation

EJ Moding, MB Kastan, DG Kirsch - Nature reviews Drug discovery, 2013 - nature.com
Approximately 50% of all patients with cancer receive radiation therapy at some point during
the course of their treatment, and the majority of these patients are treated with curative …

Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer

R Shukla, N Chanda, A Zambre… - Proceedings of the …, 2012 - National Acad Sciences
Systemic delivery of therapeutic agents to solid tumors is hindered by vascular and
interstitial barriers. We hypothesized that prostate tumor specific epigallocatechin-gallate …

Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF1R activation

J Tommelein, E De Vlieghere, L Verset, E Melsens… - Cancer research, 2018 - AACR
Preoperative radiotherapy (RT) is a mainstay in the management of rectal cancer, a tumor
characterized by desmoplastic stroma containing cancer-associated fibroblasts (CAF) …

Radiation fibrosis syndrome: neuromuscular and musculoskeletal complications in cancer survivors

MD Stubblefield - PM&R, 2011 - Elsevier
Radiation-induced toxicity is a major cause of long-term disability after cancer treatment.
Radiation fibrosis describes the insidious pathologic fibrotic tissue sclerosis that can occur in …

Recent advances in radiation therapy and photodynamic therapy

LM Chong, DJH Tng, LLY Tan, MLK Chua… - Applied Physics …, 2021 - pubs.aip.org
In the past 100 years, external beam energy for the treatment of cancer has continually
evolved. Two main modes have been developed. The first is radiotherapy which involves …

[HTML][HTML] Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers

KJ Harrington, LJ Billingham, TB Brunner… - British journal of …, 2011 - nature.com
There is a growing appreciation of the potential value of combining novel molecularly-
targeted drugs with radiotherapy or chemoradiotherapy. Such approaches have the …

[HTML][HTML] Combined hyperthermia and radiotherapy for the treatment of cancer

P Kaur, MD Hurwitz, S Krishnan, A Asea - Cancers, 2011 - mdpi.com
Radiotherapy is used to treat approximately 50% of all cancer patients, with varying success.
Radiation therapy has become an integral part of modern treatment strategies for many …