Molecular mechanisms of cancer development in obesity
MJ Khandekar, P Cohen, BM Spiegelman - Nature Reviews Cancer, 2011 - nature.com
The increasing incidence of obesity and its co-morbid conditions poses a great challenge to
global health. In addition to cardiovascular disease and diabetes, epidemiological data …
global health. In addition to cardiovascular disease and diabetes, epidemiological data …
Obesity and cancer: the role of dysfunctional adipose tissue
RCM Van Kruijsdijk, E Van Der Wall… - … , biomarkers & prevention, 2009 - AACR
Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …
[HTML][HTML] Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies
SC Larsson, A Wolk - The American journal of clinical nutrition, 2007 - Elsevier
Background: Whereas obesity has been associated with an increased risk of colon cancer in
men, a weak or no association has been observed in women. Results for rectal cancer have …
men, a weak or no association has been observed in women. Results for rectal cancer have …
Advances in understanding the interrelations between leptin resistance and obesity
H Pan, J Guo, Z Su - Physiology & behavior, 2014 - Elsevier
Obesity, which has developed into a global epidemic, is a risk factor in most chronic
diseases and some forms of malignancy. The discovery of leptin in 1994 has opened a new …
diseases and some forms of malignancy. The discovery of leptin in 1994 has opened a new …
The role of obesity and related metabolic disturbances in cancers of the colon, prostate, and pancreas
E Giovannucci, D Michaud - Gastroenterology, 2007 - Elsevier
Recent evidence indicates that obesity and related metabolic abnormalities are associated
with increased incidence or mortality for a number of cancers, including those of the colon …
with increased incidence or mortality for a number of cancers, including those of the colon …
Obesity and cancer: symposium on 'Diet and cancer'
T Pischon, U Nöthlings, H Boeing - Proceedings of the Nutrition …, 2008 - cambridge.org
The prevalence of obesity, defined as a BMI of≥ 30· 0 kg/m2, has increased substantially
over previous decades to about 20% in industrialized countries, and a further increase is …
over previous decades to about 20% in industrialized countries, and a further increase is …
Mechanisms of obesity-induced gastrointestinal neoplasia
JO Alemán, LH Eusebi, L Ricciardiello, K Patidar… - Gastroenterology, 2014 - Elsevier
Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and
associated disorders, including gastrointestinal cancers, have high morbidity and mortality …
associated disorders, including gastrointestinal cancers, have high morbidity and mortality …
[HTML][HTML] Obesity and colorectal cancer: role of adipokines in tumor initiation and progression
S Riondino, M Roselli, R Palmirotta… - World journal of …, 2014 - ncbi.nlm.nih.gov
Obesity-associated diseases account for a large portion of public health challenges. Among
obesity-related disorders, a direct and independent relationship has been ascertained for …
obesity-related disorders, a direct and independent relationship has been ascertained for …
Obesity, energy balance, and cancer: new opportunities for prevention
SD Hursting, J DiGiovanni, AJ Dannenberg… - Cancer prevention …, 2012 - AACR
Obesity is associated with increased risk and poor prognosis for many types of cancer. The
mechanisms underlying the obesity-cancer link are becoming increasingly clear and provide …
mechanisms underlying the obesity-cancer link are becoming increasingly clear and provide …