Amorphous solid dispersions stabilized by one or more polymer (s) have been widely used
for delivering amorphous drugs with poor water solubilities, and they have gained great …

In the pharmaceutical industry, poorly water-soluble drugs require enabling technologies to
increase apparent solubility in the biological environment. Amorphous solid dispersion …

Amorphous solid dispersion (ASD) is a formulation strategy extensively used to enhance the
bioavailability of poorly water soluble drugs. Despite this, they are limited by various factors …

Understanding the long-term stability of amorphous solid dispersions (ASDs) is important for
their successful approval for market. ASD stability does not only depend on the interplay …

Amorphous–Amorphous phase separation (AAPS) is an important phenomenon that can
impede the performance of amorphous solid dispersions (ASDs). The purpose of this study …

The preparation of amorphous solid dispersions (ASDs) is a well-established strategy for
formulating active pharmaceutical ingredients by embedding them in excipients, usually …

Novel polymeric carriers for amorphous solid dispersions (ASDs) are highly demanded in
pharmaceutical industry to improve the bioavailability of poorly-soluble drug candidates …

The aim of this study is to investigate the potential of hybrid polymer-lipid microparticles with
a biphasic structure (b-MPs) as drug delivery system. Hybrid b-MPs of Compritol® 888 ATO …

This paper presents a rational workflow for developing enabling formulations, such as
amorphous solid dispersions, via hot-melt extrusion in less than a year. First, our approach …

Amorphous solid dispersions (ASDs) can phase separate in the gel phase during
dissolution, lowering the chemical potential and thus the driving force for drug release. The …