What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis

A Abad, JV Fernández-Molina, J Bikandi… - Revista iberoamericana …, 2010 - Elsevier
Aspergillus fumigatus is an opportunistic pathogen that causes 90% of invasive aspergillosis
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …

[HTML][HTML] The 'amoeboid predator-fungal animal virulence'hypothesis

A Casadevall, MS Fu, AJ Guimaraes, P Albuquerque - Journal of Fungi, 2019 - mdpi.com
The observation that some aspects of amoeba-fungal interactions resemble animal
phagocytic cell-fungal interactions, together with the finding that amoeba passage can …

LaeA, a regulator of morphogenetic fungal virulence factors

JW Bok, SA Balajee, KA Marr, D Andes… - Eukaryotic …, 2005 - Am Soc Microbiol
Opportunistic animal and plant pathogens, well represented by the genus Aspergillus, have
evolved unique mechanisms to adapt to and avoid host defenses. Aspergillus fumigatus, an …

Correlation between Gliotoxin Production and Virulence of Aspergillus fumigatus in Galleria mellonella

EP Reeves, CGM Messina, S Doyle, K Kavanagh - Mycopathologia, 2004 - Springer
Aspergillus fumigatus is a pathogenic fungus capable of causing both allergic lung disease
and invasive aspergillosis, a serious, life-threatening condition in neutropenic patients …

[HTML][HTML] Aspergillus fumigatus inhibits Pseudomonas aeruginosa in co-culture: implications of a mutually antagonistic relationship on virulence and inflammation in the …

E Reece, S Doyle, P Greally, J Renwick… - Frontiers in …, 2018 - frontiersin.org
Many cystic fibrosis (CF) airway infections are considered to be polymicrobial and microbe–
microbe interactions may play an important role in disease pathology. Pseudomonas …

Aspergillus mycotoxins and their effect on the host

K Kamei, A Watanabe - Medical mycology, 2005 - academic.oup.com
Aspergillus fumigatus is known to produce various immunosuppressive mycotoxins
including gliotoxin. However, none of these mycotoxins has been confirmed as being …

Aspergillus Cyclooxygenase-Like Enzymes Are Associated with Prostaglandin Production and Virulence

DI Tsitsigiannis, JW Bok, D Andes… - Infection and …, 2005 - Am Soc Microbiol
Oxylipins comprise a family of oxygenated fatty acid-derived signaling molecules that initiate
critical biological activities in animals, plants, and fungi. Mammalian oxylipins, including the …

[HTML][HTML] Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans

J Behnsen, P Narang, M Hasenberg, F Gunzer… - PLoS …, 2007 - journals.plos.org
The fungal pathogens Aspergillus fumigatus and Candida albicans are major health threats
for immune-compromised patients. Normally, macrophages and neutrophil granulocytes …

[HTML][HTML] Introduction of a bead beating step improves fungal DNA extraction from selected patient specimens

S Scharf, A Bartels, M Kondakci, K Pfeffer… - International Journal of …, 2020 - Elsevier
In immunocompromised patients a colonisation with fungi carries the risk to develop serious
invasive fungal infection. An early detection is therefore important, but not optimal hitherto …

Aspergillus fumigatus LaeA-Mediated Phagocytosis Is Associated with a Decreased Hydrophobin Layer

TRT Dagenais, SS Giles, V Aimanianda… - Infection and …, 2010 - Am Soc Microbiol
Aspergillus fumigatus is the causal agent of the life-threatening disease invasive
aspergillosis. A. fumigatus laeA deletants, aberrant in toxin biosynthesis and spore …