Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …

Abstract Interleukin-6 (IL-6) is a key immunomodulatory cytokine that affects the
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …

Human gut commensals are increasingly suggested to impact non-communicable diseases,
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …

Human ingestion of microplastics (MPs) is inevitable due to the ubiquity of MPs in various
foods and drinking water. Whether the ingestion of MPs poses a substantial risk to human …

Objectives We aimed to provide the most updated estimates on the global burden of
inflammatory bowel disease (IBD) to improve management strategies. Design We extracted …

Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four
epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence …

Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …

The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …

Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …