Bacterial capsules: Occurrence, mechanism, and function
S Gao, W Jin, Y Quan, Y Li, Y Shen, S Yuan… - npj Biofilms and …, 2024 - nature.com
In environments characterized by extended multi-stress conditions, pathogens develop a
variety of immune escape mechanisms to enhance their ability to infect the host. The …
variety of immune escape mechanisms to enhance their ability to infect the host. The …
Synthetic genetic oscillators demonstrate the functional importance of phenotypic variation in pneumococcal-host interactions
AS Rueff, R Van Raaphorst, SD Aggarwal… - Nature …, 2023 - nature.com
Phenotypic variation is the phenomenon in which clonal cells display different traits even
under identical environmental conditions. This plasticity is thought to be important for …
under identical environmental conditions. This plasticity is thought to be important for …
Streptococcal peptides and their roles in host-microbe interactions
ER Wahlenmayer, DE Hammers - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The genus Streptococcus encompasses many bacterial species that are associated with
hosts, ranging from asymptomatic colonizers and commensals to pathogens with a …
hosts, ranging from asymptomatic colonizers and commensals to pathogens with a …
Discovery of unannotated small open reading frames in Streptococcus pneumoniae D39 involved in quorum sensing and virulence using ribosome profiling
I Laczkovich, K Mangano, X Shao, AJ Hockenberry… - MBio, 2022 - Am Soc Microbiol
Streptococcus pneumoniae, an opportunistic human pathogen, is the leading cause of
community-acquired pneumonia and an agent of otitis media, septicemia, and meningitis …
community-acquired pneumonia and an agent of otitis media, septicemia, and meningitis …
Environmental and genetic regulation of Streptococcus pneumoniae galactose catabolic pathways
BO Kareem, O Gazioglu, K Mueller Brown… - Nature …, 2024 - nature.com
Efficient utilization of nutrients is crucial for microbial survival and virulence. The same
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …
Identification and characterization of negative regulators of rgg1518 quorum sensing in streptococcus pneumoniae
D Hu, I Laczkovich, MJ Federle… - Journal of …, 2023 - Am Soc Microbiol
Streptococcus pneumoniae is an agent of otitis media, septicemia, and meningitis and
remains the leading cause of community-acquired pneumonia regardless of vaccine use. Of …
remains the leading cause of community-acquired pneumonia regardless of vaccine use. Of …
Peptide maturation molecules act as molecular gatekeepers to coordinate cell-cell communication in Streptococcus pneumoniae
KM Brown, R Eutsey, O Gazioglu, D Wang, A Vallon… - Cell Reports, 2024 - cell.com
The human pathogen Streptococcus pneumoniae (Spn) encodes several cell-cell
communication systems, notably multiple members of the Rgg/SHP and the Tpr/Phr families …
communication systems, notably multiple members of the Rgg/SHP and the Tpr/Phr families …
Biological puzzles solved by using Streptococcus pneumoniae: a historical review of the pneumococcal studies that have impacted medicine and shaped molecular …
NL Hiller, CJ Orihuela - Journal of Bacteriology, 2024 - Am Soc Microbiol
The major human pathogen Streptococcus pneumoniae has been the subject of intensive
clinical and basic scientific study for over 140 years. In multiple instances, these efforts have …
clinical and basic scientific study for over 140 years. In multiple instances, these efforts have …
Cooperation of quorum sensing and central carbon metabolism in the pathogenesis of Gram-positive bacteria
S Gao, Y Wang, S Yuan, J Zuo, W Jin, Y Shen… - Microbiological …, 2024 - Elsevier
Quorum sensing (QS), an integral component of bacterial communication, is essential in
coordinating the collective response of diverse bacterial pathogens. Central carbon …
coordinating the collective response of diverse bacterial pathogens. Central carbon …
Structure‐function analysis for the development of peptide inhibitors for a Gram‐positive quorum sensing system
IT Abdullah, AT Ulijasz, UV Girija, S Tam… - Molecular …, 2022 - Wiley Online Library
Abstract The Streptococcus pneumoniae Rgg144/SHP144 regulator‐peptide quorum
sensing (QS) system is critical for nutrient utilization, oxidative stress response, and …
sensing (QS) system is critical for nutrient utilization, oxidative stress response, and …