Investigational approaches for treatment of melanoma patients progressing after standard of care

KA Fletcher, DB Johnson - The Cancer Journal, 2024 - journals.lww.com
The advent of effective immunotherapy, specifically cytotoxic T-lymphocyte associated
protein 4 and programmed cell death 1 inhibitors, as well as targeted therapy including …

Spatially Fractionated Radiotherapy in the Era of Immunotherapy

MT McMillan, AJ Khan, SN Powell, J Humm… - Seminars in Radiation …, 2024 - Elsevier
Spatially fractionated radiotherapy (SFRT) includes historical grid therapy approaches but
more recently encompasses the controlled introduction of one or more cold dose regions …

[HTML][HTML] Reconciling the discrepancies in randomized data of combining immunotherapy and radiation therapy: Not all radiotherapy is created equal

JY Chang, V Verma, RR Weichselbaum - European Journal of Cancer, 2024 - Elsevier
It remains highly unclear and debatable whether combining radiotherapy (RT) and immune
checkpoint blocker (ICB) therapy yields improved outcomes compared to either modality …

A Partial Tumor Irradiation Approach for Complex Bulky Disease

S Tubin - Seminars in Radiation Oncology, 2024 - Elsevier
A large proportion of cancer patients present with unresectable bulky disease at baseline or
following treatment failure. The data available in the literature suggest that the vast majority …

Advances in the Treatment of Pulmonary Nodules

Q Zhang, X Wu, H Yang, P Luo, N Wei, S Wang, X Zhao… - Respiration, 2024 - karger.com
Background: Early detection and accurate diagnosis of pulmonary nodules are crucial for
improving patient outcomes. While surgical resection of malignant nodules is still the …

[HTML][HTML] Is Single-Site Radiation Therapy Enough to Augment the Immune System and Enhance Immunotherapy for Metastatic Disease?

V Verma, HB Barsoumian, JW Welsh - Seminars in Radiation Oncology, 2024 - Elsevier
Despite the promise of combining immunotherapy and radiotherapy (RT) for metastatic
cancers, existing randomized data have not been consistent on whether RT to a single …

[HTML][HTML] Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma

RC Augustin, S Newman, A Li, M Joy… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Acral melanoma (AM) has distinct characteristics as compared with cutaneous melanoma
and exhibits poor response to immune checkpoint inhibitors (ICIs). Tumor-intrinsic …

Immunotherapy for Solitary Fibrous Tumor (Hemangiopericytoma): A Unique Treatment Approach for a Rare Central Nervous System Tumor

L Singer, J Singer, C Horbinski, M Penas-Prado… - The …, 2024 - journals.lww.com
Immunotherapy for Solitary Fibrous Tumor (Hemangiopericytoma) Page 1 Immunotherapy for
Solitary Fibrous Tumor (Hemangiopericytoma) A Unique Treatment Approach for a Rare …

Advances in the Treatment of Pulmonary Nodules

QZXWH Yanga, PLN Weia - 2024 - karger.com
Background: Early detection and accurate diagnosis of pulmonary nodules are crucial for
improving patient outcomes. While surgical resection of malignant nodules is still the …

Harnessing Bacterial Membrane Components for Tumor Vaccines: Strategies and Perspectives

Z Bai, X Wang, T Liang, G Xu, J Cai, W Xu… - Advanced Healthcare … - Wiley Online Library
Tumor vaccines stand at the vanguard of tumor immunotherapy, demonstrating significant
potential and promise in recent years. While tumor vaccines have achieved breakthroughs …