Colon-targeted delivery of polyphenols: construction principles, targeting mechanisms and evaluation methods

Y Wang, Z Li, Y Bao, H Cui, J Li, B Song… - Critical Reviews in …, 2023 - Taylor & Francis
Polyphenols have received considerable attention for their promotive effects on colonic
health. However, polyphenols are mostly sensitive to harsh gastrointestinal environments …

Oral delivery of porous starch-loaded bilayer microgels for controlled drug delivery and treatment of ulcerative colitis

Z Wen, L Kang, H Fu, S Zhu, X Ye, X Yang… - Carbohydrate …, 2023 - Elsevier
We prepared one type of bilayer microgels for oral administration with three effects: pH
responsiveness, time lag, and colon enzyme degradation. Combined with the dual …

Advancing gastrointestinal health: curcumin's efficacy and nanopreparations

J Ji, Z Ma, Y Wang - Molecules, 2024 - mdpi.com
Curcumin (CCM) is a polyphenol compound extracted from the turmeric rhizome. It has
various biological activities, including antibacterial, anti-inflammatory, anti-cancer, and …

Study of anti-inflammatory and anti-arthritic potential of curcumin-loaded Eudragit L100 and hydroxy propyl methyl cellulose (HPMC) microparticles

SR Rajpoot, K Ahmad, HM Asif, MA Madni… - Polymer Bulletin, 2024 - Springer
Curcumin is derived from Curcuma longa's dried root rhizomes possessing extensive variety
of therapeutic actions such as antifungal, anti-inflammatory, antibacterial, antispasmodic …

Effects of polyphenolic maqui (Aristotelia chilensis) extract on the inhibition of NLRP3 inflammasome and activation of mast cells in a mouse model of Crohn's disease …

T Ortiz-Cerda, F Argüelles-Arias… - Frontiers in …, 2024 - frontiersin.org
Introduction Crohn's disease (CD) involves activation of mast cells (MC) and NF-кB in
parallel with the PPAR-α/NLRP3 inflammasome/IL-1β pathway in the inflamed colon …

Therapeutic and prophylactic role of vitamin D and curcumin in acetic acid-induced acute ulcerative colitis model

AS Erarslan, R Ozmerdivenli, F Sirinyıldız… - Toxicology …, 2023 - Taylor & Francis
Ulcerative Colitis (UC) is a disease that negatively affects quality of life and is associated
with sustained oxidative stress, inflammation and intestinal permeability. Vitamin D and …

[HTML][HTML] Therapeutic potential of Capparis spinosa in experimental model of acute acetic acid-induced colitis: Anti-inflammatory and antioxidant effects

F HosseiniRavesh, AAM Ghalibaf, VR Askari… - Heliyon, 2024 - Elsevier
Introduction This study examined the anti-inflammatory and antioxidant properties of
Capparis spinosa L.(caper) in order to determine its medicinal potential in the treatment of …

[PDF][PDF] Effect of Bioresorbable Copolymers on Mesalamine Loaded Microspheres for Colon-Specific Drug Delivery.

N Madhavi, B Divya, B Sudhakar… - International Journal of …, 2024 - academia.edu
Background: Mesalamine produces many side effects through oral route such as stomach
cramps, throat irritation, back ache and muscle pain. Furthermore, it failed to yield maximum …

Therapeutic Potential of Capparis spinosa in Experimental model of Acute Acetic Acid-Induced Colitis: Anti-inflammatory and Antioxidant Effects

AAM Ghalibaf, VR Askari, F Fayedeh, VB Rahimi… - Heliyon - cell.com
Introduction This study examined the anti-inflammatory and antioxidant properties of
Capparis spinosa L.(caper) in order to determine its medicinal potential in the treatment of …