Proteins that bind both DNA and RNA typify the ability of a single gene product to perform
multiple functions. Such DNA-and RNA-binding proteins (DRBPs) have unique functional …

Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

Abstract Web 3DNA (w3DNA) 2.0 is a significantly enhanced version of the widely used
w3DNA server for the analysis, visualization, and modeling of 3D nucleic-acid-containing …

Computational docking is the prediction or modeling of the three-dimensional structure of a
biomolecular complex, starting from the structures of the individual molecules in their free …

Mitochondria have specialized ribosomes that have diverged from their bacterial and
cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large …

The highly divergent ribosomes of human mitochondria (mitoribosomes) synthesize 13
essential proteins of oxidative phosphorylation complexes. We have determined the …

Recognition of DNA by the innate immune system is central to antiviral and antibacterial
defenses, as well as an important contributor to autoimmune diseases involving self DNA …

Human mitochondrial ribosomes are highly divergent from all other known ribosomes and
are specialized to exclusively translate membrane proteins. They are linked with hereditary …

Insight into the three-dimensional architecture of RNA is essential for understanding its
cellular functions. However, even the classic transfer RNA structure contains features that …

Functional nucleic acid (FNA) nanotechnology is an interdisciplinary field between nucleic
acid biochemistry and nanotechnology that focuses on the study of interactions between …