Comparative effectiveness of first-line medications for primary open-angle glaucoma: a systematic review and network meta-analysis

T Li, K Lindsley, B Rouse, H Hong, Q Shi, DS Friedman… - Ophthalmology, 2016 - Elsevier
Topic Primary open-angle glaucoma (POAG) is a highly prevalent condition worldwide and
the most common cause of irreversible sight loss. The objective is to assess the comparative …

Fixed-combination intraocular pressure-lowering therapy for glaucoma and ocular hypertension: advantages in clinical practice

G Holló, F Topouzis, RD Fechtner - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: Several large, randomized, prospective clinical trials have demonstrated that
medical therapy to reduce intraocular pressure (IOP) delays the onset and decreases …

Network meta-analysis for clinical practice guidelines: a case study on first-line medical therapies for primary open-angle glaucoma

B Rouse, A Cipriani, Q Shi, AL Coleman… - Annals of internal …, 2016 - acpjournals.org
Background: Network meta-analysis compares multiple treatment options for the same
condition and may be useful for developing clinical practice guidelines. Purpose: To …

Current and emerging fixed combination therapies in glaucoma: a safety and tolerability review

AG Konstas, L Schmetterer, VP Costa… - Expert opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction Fixed dose combinations (FCs) represent a potentially valuable
treatment strategy in glaucoma management. Fixed combinations not only improve …

[HTML][HTML] Efficacy and safety of brinzolamide as add-on to prostaglandin analogues or β-blocker for glaucoma and ocular hypertension: a systematic review and meta …

Y Liu, J Zhao, X Zhong, Q Wei, Y Huang - Frontiers in Pharmacology, 2019 - frontiersin.org
Background: Brinzolamide as a carbonic anhydrase inhibitor could be combined with other
intraocular pressure (IOP) lowering drugs for glaucoma and ocular hypertension (OHT), but …

Evaluation of the effects on choroidal thickness of bimatoprost 0.03% versus a brinzolamide 1.0%/timolol maleate 0.5% fixed combination

N Akyol, A Kalkisim, A Turk, M Kola… - Cutaneous and Ocular …, 2017 - Taylor & Francis
Objective: To investigate the effects of two different medical treatment options on choroidal
thickness (CT) in cases of open-angle glaucoma (OAG). Methods: Sixty-seven eyes newly …

Identification and management of glaucoma

S Mamtora, D Leadbetter, D Atan - Prescriber, 2022 - Wiley Online Library
Glaucoma is the leading cause of irreversible blindness and the aim of all glaucoma
treatments is to lower intraocular pressure (IOP), the only modifiable risk factor. This article …

Daily costs and cost effectiveness of glaucoma fixed combinations in China

C Xu, R Guo, D Huang, J Ji, W Liu - Journal of Ophthalmology, 2020 - Wiley Online Library
Background. The aim of this study was to compare the daily costs and cost effectiveness of
fixed combination glaucoma drugs in China. Methods. This study included the following …

[HTML][HTML] A randomized trial of fixed-dose combination brinzolamide 1%/brimonidine 0.2% as adjunctive therapy to travoprost 0.004%

RM Feldman, G Katz, M McMenemy… - American Journal of …, 2016 - Elsevier
Purpose To evaluate the safety and efficacy of adding fixed-combination brinzolamide
1%/brimonidine 0.2%(BBFC) as adjunctive therapy to travoprost 0.004%(TRAV) in patients …

Combination of brinzolamide and brimonidine for glaucoma and ocular hypertension: critical appraisal and patient focus

QH Nguyen - Patient preference and adherence, 2014 - Taylor & Francis
Glaucoma is one of the leading causes of blindness and is characterized by optic nerve
damage that results in visual field loss. Elevated intraocular pressure (IOP) has been …