[HTML][HTML] Metabolic syndrome-related kidney injury: a review and update

L Lin, W Tan, X Pan, E Tian, Z Wu… - Frontiers in endocrinology, 2022 - frontiersin.org
Metabolic syndrome (MetS) includes visceral obesity, hyperglycemia, dyslipidemia, and
hypertension. The prevalence of MetS is 20-25%, which is an important risk factor for chronic …

[HTML][HTML] Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention.

E Almanza-Aguilera, A Cano, M Gil-Lespinard… - Seminars in Cancer …, 2023 - Elsevier
Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …

Plasma cell-free DNA predicts survival and maps specific sources of injury in pulmonary arterial hypertension

SB Brusca, JM Elinoff, Y Zou, MK Jang, H Kong… - Circulation, 2022 - Am Heart Assoc
Background: Cell-free DNA (cfDNA) is a noninvasive marker of cellular injury. Its
significance in pulmonary arterial hypertension (PAH) is unknown. Methods: Plasma cfDNA …

[HTML][HTML] Obesity: The fat tissue disease version of cancer

B Boubertakh, C Silvestri, V Di Marzo - Cells, 2022 - mdpi.com
Obesity is a disease with high potential for fatality. It perfectly fits the disease definition, as
cancer does. This is because it damages body structure and functions, both mechanically …

Reassessing the causal role of obesity in breast cancer susceptibility: a comprehensive multivariable Mendelian randomization investigating the distribution and …

Y Hao, J Xiao, Y Liang, X Wu, H Zhang… - International journal …, 2023 - academic.oup.com
Abstract Background Previous Mendelian randomization (MR) studies on obesity and risk of
breast cancer adopted a small number of instrumental variables and focused mainly on the …

[HTML][HTML] Sex differences in adiposity and cardiovascular diseases

H Li, D Konja, L Wang, Y Wang - International Journal of Molecular …, 2022 - mdpi.com
Body fat distribution is a well-established predictor of adverse medical outcomes,
independent of overall adiposity. Studying body fat distribution sheds insights into the …

[HTML][HTML] Hormones and sex-specific medicine in human physiopathology

MR Tokatli, LG Sisti, E Marziali, L Nachira, MF Rossi… - Biomolecules, 2022 - mdpi.com
A prodigious increment of scientific evidence in both preclinical and clinical studies is
narrowing a major gap in knowledge regarding sex-specific biological responses observed …

[HTML][HTML] Obesity-induced thymic involution and cancer risk

MK Lagou, GS Karagiannis - Seminars in Cancer Biology, 2023 - Elsevier
Declining thymic functions associated either with old age (ie, age-related thymic involution),
or with acute involution as a result of stress, infectious disease, or cytoreductive therapies …

Interplay between Estrogen, Kynurenine, and AHR Pathways: An immunosuppressive axis with therapeutic potential for breast cancer treatment

JHL Pacheco, G Elizondo - Biochemical Pharmacology, 2023 - Elsevier
Breast cancer is one of the most common malignancies among women worldwide. Estrogen
exposure via endogenous and exogenous sources during a lifetime, together with …

[HTML][HTML] Obesity amplifies influenza virus-driven disease severity in male and female mice

PC Alarcon, MSMA Damen, CJ Ulanowicz… - Mucosal …, 2023 - Elsevier
Influenza virus-induced respiratory pneumonia remains a major public health concern.
Obesity, metabolic diseases, and female sex are viewed as independent risk factors for …