Thyroid disease in pregnancy: new insights in diagnosis and clinical management

TIM Korevaar, M Medici, TJ Visser… - Nature Reviews …, 2017 - nature.com
Adequate thyroid hormone availability is important for an uncomplicated pregnancy and
optimal fetal growth and development. Overt thyroid disease is associated with a wide range …

Subclinical hypothyroidism in pregnancy: a systematic review and meta-analysis

S Maraka, NMS Ospina, DT O'Keeffe… - Thyroid, 2016 - liebertpub.com
Background: The impact of subclinical hypothyroidism (SCH) and of levothyroxine
replacement in pregnant women with SCH is unclear. The aims of this study were to assess …

Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment

S Maraka, R Mwangi, RG McCoy, X Yao… - Bmj, 2017 - bmj.com
Objective To estimate the effectiveness and safety of thyroid hormone treatment among
pregnant women with subclinical hypothyroidism. Design Retrospective cohort study. Setting …

Thyroid function in pregnancy: what is normal?

M Medici, TIM Korevaar, WE Visser, TJ Visser… - Clinical …, 2015 - academic.oup.com
BACKGROUND Gestational thyroid dysfunction is common and associated with maternal
and child morbidity and mortality. During pregnancy, profound changes in thyroid physiology …

Patients with subclinical hypothyroidism before 20 weeks of pregnancy have a higher risk of miscarriage: A systematic review and meta-analysis

Y Zhang, H Wang, X Pan, W Teng, Z Shan - PloS one, 2017 - journals.plos.org
Objective To evaluate the relationship between subclinical hypothyroidism (SCH) and the
risk of miscarriage before 20 weeks of pregnancy. Methods Literature databases were …

Levothyroxine treatment of mild subclinical hypothyroidism: a review of potential risks and benefits

Z Javed, T Sathyapalan - Therapeutic advances in …, 2016 - journals.sagepub.com
Subclinical hypothyroidism (SCH) is defined as elevated thyroid stimulating hormone (TSH)
with normal levels of free triiodothyronine (FT3) and free thyroxine (FT4). SCH is further …

Managing thyroid disease in general practice

JP Walsh - Medical Journal of Australia, 2016 - Wiley Online Library
Serum thyroid‐stimulating hormone (TSH) testing is the best screening tool for thyroid
dysfunction. When TSH levels are in the reference range, additional tests such as free …

Restless legs syndrome and pregnancy: prevalence, possible pathophysiological mechanisms and treatment

R Gupta, M Dhyani, T Kendzerska… - Acta Neurologica …, 2016 - Wiley Online Library
Restless legs syndrome (RLS) is a common sleep disorder that may be associated with
pregnancy. Studies have found that the prevalence of RLS among pregnant women ranged …

Impact of levothyroxine therapy on obstetric, neonatal and childhood outcomes in women with subclinical hypothyroidism diagnosed in pregnancy: a systematic …

JM Yamamoto, JL Benham, KA Nerenberg… - BMJ open, 2018 - bmjopen.bmj.com
Objective To determine in women with subclinical hypothyroidism diagnosed in pregnancy
whether levothyroxine treatment compared with control, impacts important obstetrical or …

Maternal TSH level and TPOAb status in early pregnancy and their relationship to the risk of gestational diabetes mellitus

H Ying, YP Tang, YR Bao, XJ Su, XY Cai, YH Li… - Endocrine, 2016 - Springer
Subclinical hypothyroidism is common in pregnant women and often related to adverse
pregnancy outcomes, but its relationship with gestational diabetes remains controversial. In …