Activatable Probes for Ratiometric Imaging of Endogenous Biomarkers In Vivo

Q Fu, X Yang, M Wang, K Zhu, Y Wang, J Song - ACS nano, 2024 - ACS Publications
Dynamic variations in the concentration and abnormal distribution of endogenous
biomarkers are strongly associated with multiple physiological and pathological states …

Three Strategies in Engineering Nanomedicines for Tumor Microenvironment‐Enabled Phototherapy

S He, X Jia, S Feng, J Hu - Small, 2023 - Wiley Online Library
Canonical phototherapeutics have several limitations, including a lack of tumor selectivity,
nondiscriminatory phototoxicity, and tumor hypoxia aggravation. The tumor …

[HTML][HTML] Hydrogen sulfide and its donors for the treatment of cerebral ischaemia-reperfusion injury: A comprehensive review

Y Huang, M Omorou, M Gao, C Mu, W Xu… - Biomedicine & …, 2023 - Elsevier
As an endogenous gas signalling molecule, hydrogen sulfide (H 2 S) is frequently present in
a variety of mammals and plays a significant role in the cardiovascular and nervous systems …

Who is in the driver's seat? Parvimonas micra: An understudied pathobiont at the crossroads of dysbiotic disease and cancer

DL Higashi, MC Krieger, H Qin, Z Zou… - Environmental …, 2023 - Wiley Online Library
Recent advances in our understanding of microbiome composition at sites of inflammatory
dysbiosis have triggered a substantial interest in a variety of historically understudied …

The emerging key role of reactive sulfur species in abiotic stress tolerance in plants

AF Alvi, N Iqbal, M Albaqami, NA Khan - Physiologia Plantarum, 2023 - Wiley Online Library
In plants, sulfur plays a critical role in the formation of important biomolecules such as
cysteine, methionine, and tripeptide glutathione. Thiol groups, composed of sulfur, are …

Exhaled biomarkers for point-of-care diagnosis: Recent advances and new challenges in breathomics

H Kiss, Z Örlős, Á Gellért, Z Megyesfalvi, A Mikáczó… - Micromachines, 2023 - mdpi.com
Cancers, chronic diseases and respiratory infections are major causes of mortality and
present diagnostic and therapeutic challenges for health care. There is an unmet medical …

A Golgi-targeted fluorescent probe for imaging H2O2 and releasing H2S during Golgi stress

F Liu, X Zhang, J Jing, X Zhang - Dyes and Pigments, 2023 - Elsevier
Golgi stress was the major stress response in the Golgi apparatus, which might be induced
the disruption of redox balance and relate to a variety of diseases. As an important reactive …

The double-edged sword role of hydrogen sulfide in hepatocellular carcinoma

H Zhao, Y Zhang, X Fu, C Chen, S Khattak… - Frontiers in …, 2023 - frontiersin.org
With an increasing worldwide prevalence, hepatocellular carcinoma (HCC) is the most
common primary malignant tumor of the liver in the world. It is also the primary reason for …

Sequential accumulation of 'driver'pathway mutations induces the upregulation of hydrogen-sulfide-producing enzymes in human colonic epithelial cell organoids

K Ascenção, N Dilek, K Zuhra, K Módis, T Sato… - Antioxidants, 2022 - mdpi.com
Recently, a CRISPR-Cas9 genome-editing system was developed with introduced
sequential 'driver'mutations in the WNT, MAPK, TGF-β, TP53 and PI3K pathways into …

Recent advances in the role of endogenous hydrogen sulphide in cancer cells

HJ Chen, K Li, YZ Qin, JJ Zhou, T Li, L Qian… - Cell …, 2023 - Wiley Online Library
Hydrogen sulphide (H2S) is a gaseous neurotransmitter that can be self‐synthesized by
living organisms. With the deepening of research, the pathophysiological mechanisms of …