Влияние антигипертензивной терапии валсартаном и его фиксированной комбинации с гидрохлоротиазидом на скорость пульсовой волны и центральное …

ИЕ Чазова, ТВ Мартынюк, МВ Архипов… - Системные …, 2018 - cyberleninka.ru
Цель исследования изучить влияние валсартана в виде монотерапии и его комбинации
с гидрохлоротиазидом (ГХТ) на скорость пульсовой волны (СПВ) и центральное …

[PDF][PDF] Cardiovascular effects of the combination of levosimendan and valsartan in hypertensive Dahl/Rapp rats

A Biala, P Finckenberg, A Korpi, M Loytainen… - Journal of Physiology …, 2011 - jpp.krakow.pl
Hypertension is the main risk factor for left ventricular hypertrophy and development of
diastolic heart failure. There is no yet treatment, which can effectively reduce mortality in …

Valsartan inhibits angiotensin II-induced proliferation of vascular smooth muscle cells via regulating the expression of mitofusin 2

H Liao, J Gong, W Zhang, X Guo - … of Huazhong University of Science and …, 2012 - Springer
Angiotensin II (ANGII) plays an important role in the pathogenesis of atherosclerosis by
inducing proliferation of vascular smooth muscle cells (VSMCs). In our study, we observed …

[HTML][HTML] The effects of valsartan on renal glutathione peroxidase expression in alleviation of cyclosporine nephrotoxicity in rats

S Raeisi, A Ghorbanihaghjo, H Argani… - BioImpacts …, 2016 - ncbi.nlm.nih.gov
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Introduction: Nephrotoxicity as a side effect caused by the immunosuppressive drug …

Sensitive HPLC method with fluorescence detection and on-line wavelength switching for simultaneous determination of valsartan and amlodipine in human plasma

NY Khalil, TA Wani, MA Abunassif… - Journal of liquid …, 2011 - Taylor & Francis
This study describes the development and validation of a highly sensitive high-performance
liquid chromatographic method with fluorescence detection and on-line emission …

Valsartan: in children and adolescents with hypertension

JD Croxtall - Pediatric Drugs, 2012 - Springer
Valsartan is an oral angiotensin II subtype 1 receptor antagonist with well established
antihypertensive efficacy in adults. It is now approved in the EU and the US for the treatment …

[PDF][PDF] Efficacy of Fixed-Dose Combination Therapy in the Treatment of Patients with Hypertension

PM Da Silva - Clin Drug Investig, 2010 - core.ac.uk
Early initiation of rational and effective combination therapy consisting of antihypertensive
drugs with two different and complementary mechanisms of actions is increasingly …

A drug safety evaluation of valsartan

R Fogari, A Zoppi - Expert Opinion on Drug Safety, 2011 - Taylor & Francis
Introduction: Angiotensin receptor blockers (ARBs) as a class are generally considered safe
and better tolerated than other antihypertensive drugs. The purpose of this report is to review …

The effects of valsartan on renal klotho expression and oxidative stress in alleviation of cyclosporine nephrotoxicity

S Raeisi, A Ghorbanihaghjo, H Argani… - …, 2021 - journals.lww.com
Background Nephrotoxicity side effect of the immunosuppressive drug, cyclosporine A
(CsA), can be a major issue in transplantation medicine. Cyclosporine A–induced …

Valsartan versus amlodipine effect on left ventricular multidirectional deformation and adipocytokines levels in hypertensive patients: speckle tracking …

I Khairat, L Khedr, R Werida - High Blood Pressure & Cardiovascular …, 2020 - Springer
Introduction Structural and functional properties of the left ventricle (LV) wall have been
reported to be altered in hypertension, even at early stages of the disease. Abnormal …