Early intervention service systems for youth mental health: integrating pluripotentiality, clinical staging, and transdiagnostic lessons from early psychosis

JL Shah, N Jones, J van Os, PD McGorry… - The Lancet …, 2022 - thelancet.com
Challenges associated with operationalising services for the at-risk mental state for
psychosis solely in that same diagnostic silo are increasingly well recognised—namely, the …

Clinical validity of DSM-5 attenuated psychosis syndrome: advances in diagnosis, prognosis, and treatment

GS De Pablo, A Catalan, P Fusar-Poli - JAMA psychiatry, 2020 - jamanetwork.com
Importance Since the release of theDSM-5diagnosis of attenuated psychosis syndrome
(DSM-5–APS) in 2013, several research studies have investigated its clinical validity …

Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry

PD McGorry, JA Hartmann, R Spooner… - World …, 2018 - Wiley Online Library
The “at risk mental state” for psychosis approach has been a catalytic, highly productive
research paradigm over the last 25 years. In this paper we review that paradigm and …

Can we reduce the duration of untreated psychosis? A systematic review and meta-analysis of controlled interventional studies

D Oliver, C Davies, G Crossland, S Lim… - Schizophrenia …, 2018 - academic.oup.com
Reduction of duration of untreated psychosis (DUP) is the key strategy of early interventions
for improving the outcomes of first-episode psychosis. Although several controlled …

Worldwide implementation of clinical services for the prevention of psychosis: the IEPA early intervention in mental health survey

M Kotlicka‐Antczak, M Podgórski… - Early intervention in …, 2020 - Wiley Online Library
Background Clinical research into the Clinical High Risk state for Psychosis (CHR‐P) has
allowed primary indicated prevention in psychiatry to improve outcomes of psychotic …

[HTML][HTML] Improving the detection of individuals at clinical risk for psychosis in the community, primary and secondary care: an integrated evidence-based approach

P Fusar-Poli, SA Sullivan, JL Shah… - Frontiers in psychiatry, 2019 - frontiersin.org
Background: The first rate-limiting step for improving outcomes of psychosis through
preventive interventions in people at clinical high risk for psychosis (CHR-P) is the ability to …

Diagnosis, prognosis, and treatment of brief psychotic episodes: a review and research agenda

P Fusar-Poli, GS De Pablo, RP Rajkumar… - The Lancet …, 2022 - thelancet.com
Brief psychotic episodes represent an intriguing paradox in clinical psychiatry because they
elude the standard knowledge that applies to the persisting psychotic disorders such as …

Dynamic ElecTronic hEalth reCord deTection (DETECT) of individuals at risk of a first episode of psychosis: a case-control development and validation study

LL Raket, J Jaskolowski, BJ Kinon… - The Lancet Digital …, 2020 - thelancet.com
Background Many individuals who will experience a first episode of psychosis (FEP) are not
detected before occurrence, limiting the effect of preventive interventions. The combination …

'At risk mental state'clinics for psychosis–an idea whose time has come–and gone!

O Ajnakina, AS David, RM Murray - Psychological medicine, 2019 - cambridge.org
At Risk Mental State (ARMS) clinics are specialised mental health services for young, help-
seeking people, thought to be at ultra-high risk of developing psychosis. Their stated …

Early intervention in psychosis in young people: a population and public health perspective

A Malla, P McGorry - American journal of public health, 2019 - ajph.aphapublications.org
Over the past two decades or more, the creation of early intervention services (EIS) for
psychoses has been regarded as one of the most significant developments in the reform of …