[HTML][HTML] Impaired AT2 to AT1 cell transition in PM2. 5-induced mouse model of chronic obstructive pulmonary disease
H Yu, Y Lin, Y Zhong, X Guo, Y Lin, S Yang, J Liu… - Respiratory …, 2022 - Springer
Abstract Background Particular matter 2.5 (PM2. 5) is one of the most important air pollutant,
and it is positively associated with the development of chronic obstructive pulmonary …
and it is positively associated with the development of chronic obstructive pulmonary …
Interfering with SARS-CoV-2: are interferons friends or foes in COVID-19?
I Zanoni - Current Opinion in Virology, 2021 - Elsevier
Type I and type III interferons are among the most potent anti-viral cytokines produced by the
immune system. The recent outbreak of SARS-CoV-2, which causes COVID-19 …
immune system. The recent outbreak of SARS-CoV-2, which causes COVID-19 …
Increased sensitivity of SARS-CoV-2 to type III interferon in human intestinal epithelial cells
C Metz-Zumaran, C Kee, P Doldan, C Guo… - Journal of …, 2022 - Am Soc Microbiol
The coronavirus SARS-CoV-2 caused the COVID-19 global pandemic leading to 5.3 million
deaths worldwide as of December 2021. The human intestine was found to be a major viral …
deaths worldwide as of December 2021. The human intestine was found to be a major viral …
[HTML][HTML] In vitro lung models and their application to study SARS-CoV-2 pathogenesis and disease
N Heinen, M Kloehn, E Steinmann, S Pfaender - Viruses, 2021 - mdpi.com
SARS-CoV-2 has spread across the globe with an astonishing velocity and lethality that has
put scientist and pharmaceutical companies worldwide on the spot to develop novel …
put scientist and pharmaceutical companies worldwide on the spot to develop novel …
[HTML][HTML] Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19
M Kiener, N Roldan, C Machahua, A Sengupta… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic has caused considerable socio-
economic burden, which fueled the development of treatment strategies and vaccines at an …
economic burden, which fueled the development of treatment strategies and vaccines at an …
[HTML][HTML] Improved SARS-CoV-2 sequencing surveillance allows the identification of new variants and signatures in infected patients
Background Genomic surveillance of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is the only approach to rapidly monitor and tackle emerging variants of …
(SARS-CoV-2) is the only approach to rapidly monitor and tackle emerging variants of …
Stem cells in pulmonary alveolar regeneration
The lungs are constantly exposed to the external environment and are therefore vulnerable
to insults that can cause infection and injury. Maintaining the integrity and barrier function of …
to insults that can cause infection and injury. Maintaining the integrity and barrier function of …
[HTML][HTML] Tropism of SARS-CoV-2 for developing human cortical astrocytes
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) readily infects a variety
of cell types impacting the function of vital organ systems, with particularly severe impact on …
of cell types impacting the function of vital organ systems, with particularly severe impact on …
[HTML][HTML] Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids
Clinical management of patients with severe complications of COVID-19 has been hindered
by a lack of effective drugs and a failure to capture the extensive heterogeneity of the …
by a lack of effective drugs and a failure to capture the extensive heterogeneity of the …
[HTML][HTML] SARS-CoV-2 membrane protein causes the mitochondrial apoptosis and pulmonary edema via targeting BOK
Y Yang, Y Wu, X Meng, Z Wang, M Younis… - Cell Death & …, 2022 - nature.com
Deaths caused by coronavirus disease 2019 (COVID-19) are largely due to the lungs
edema resulting from the disruption of the lung alveolo-capillary barrier, induced by SARS …
edema resulting from the disruption of the lung alveolo-capillary barrier, induced by SARS …