The lack of effective treatments for neurodegenerative diseases (NDs) is an important
current concern. Lipid nanoparticles can deliver innovative combinations of active molecules …

Conspectus For the delivery of drugs, different nanosized drug carriers (eg, liposomes, lipid
nanoparticles, and micelles) have been developed in order to treat diseases that afflict …

Currently, one of the most significant and rapidly growing unmet medical challenges is the
treatment of neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's …

Antimicrobial peptides (AMPs) have emerged as a promising solution to tackle bacterial
infections and combat antibiotic resistance. However, their vulnerability to protease …

Palbociclib (PBC) is an FDA-approved CDK4/6 inhibitor used for breast cancer treatment.
PBC has been demonstrated its ability to suppress the proliferation of glioma cells by …

Peptides and proteins have recently emerged as efficient therapeutic alternatives to
conventional therapies. Although they emerged a few decades back, extensive exploration …

Our previous studies demonstrated that L-octaarginine grafted onto hyaluronic acid via a
tetraglycine spacer significantly enhanced intranasal absorption of protein drugs with a …

Brain diseases are the most devastating problem among the world's increasingly aging
population, and the number of patients with neurological diseases is expected to increase in …

Neuroinflammation is a key pathophysiological feature of stroke-associated brain injury. A
local innate immune response triggers neuroinflammation following a stroke via activating …

Peptides have become an indispensable tool in engineering of multifunctional nanostructure
platforms for biomedical applications such as targeted drug and gene delivery, imaging and …