[HTML][HTML] Dietary regulation of gut-brain axis in Alzheimer's disease: Importance of microbiota metabolites

DM Frausto, CB Forsyth, A Keshavarzian… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease that impacts 45 million people
worldwide and is ranked as the 6th top cause of death among all adults by the Centers for …

The ins and outs of the caudal nucleus of the solitary tract: An overview of cellular populations and anatomical connections

MK Holt - Journal of Neuroendocrinology, 2022 - Wiley Online Library
The body and brain are in constant two‐way communication. Driving this communication is a
region in the lower brainstem: the dorsal vagal complex. Within the dorsal vagal complex …

Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy

L Guo, Z Jiang, R Sun, W Pang, M Du, M Chen… - Brain Research …, 2022 - Elsevier
The social defeat stress model is commonly used to study depression and anxiety disorder,
which can significantly affect the structure and function of neurons in the hippocampus; …

Glial modulation of energy balance: The dorsal vagal complex is no exception

JD Troadec, S Gaigé, M Barbot, B Lebrun… - International Journal of …, 2022 - mdpi.com
The avoidance of being overweight or obese is a daily challenge for a growing number of
people. The growing proportion of people suffering from a nutritional imbalance in many …

Recognizing depression as an inflammatory disease: The search for endotypes

J Steffen, N Focken, G Caliskan - American Journal of …, 2024 - journals.physiology.org
Major depressive disorder (MDD) affects millions of individuals worldwide, leading to
considerable social and economic costs. Despite advancements in pharmacological …

Vagotomy blunts cardiorespiratory responses to vagal afferent stimulation via pre‐and postsynaptic effects in the nucleus tractus solitarii

GC Hofmann, P Gama de Barcellos Filho… - The Journal of …, 2024 - Wiley Online Library
Viscerosensory information travels to the brain via vagal afferents, where it is first integrated
within the brainstem nucleus tractus solitarii (nTS), a critical contributor to cardiorespiratory …

Left cardiac vagotomy rapidly reduces contralateral cardiac vagal electrical activity in anesthetized Göttingen minipigs

F Vallone, A Dushpanova, M Leali, I Strauss… - International Journal of …, 2024 - Elsevier
Background The impact of acute unilateral injury on spontaneous electrical activity in both
vagus nerves at the heart level is poorly understood. We investigated the immediate …

Constitutively active microglial populations limit anorexia induced by the food contaminant deoxynivalenol

S Gaige, R Barbouche, M Barbot, S Boularand… - Journal of …, 2022 - Springer
Microglia are involved in neuroinflammatory processes during diverse pathophysiological
conditions. To date, the possible contribution of these cells to deoxynivalenol (DON) …

Gut microbiota-astrocyte axis: new insights into age-related cognitive decline

L Zhang, J Wei, X Liu, D Li, X Pang, F Chen… - Neural Regeneration … - journals.lww.com
With the rapidly aging human population, age-related cognitive decline and dementia are
becoming increasingly prevalent worldwide. Aging is considered the main risk factor for …

Vagus nerve manipulation and microglial plasticity in the prenatal brain

M Courchesne, C Wakefield, K Nygard, P Burns… - Vagus Nerve …, 2023 - Springer
The efferent and afferent effects of the vagus nerve on the developing brain have remained
enigmatic. Here we review the evidence of such effects on microglial plasticity in the sheep …