Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study

SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

[HTML][HTML] Lung densitometry: why, how and when

M Mascalchi, G Camiciottoli, S Diciotti - Journal of thoracic disease, 2017 - ncbi.nlm.nih.gov
Lung densitometry assesses with computed tomography (CT) the X-ray attenuation of the
pulmonary tissue which reflects both the degree of inflation and the structural lung …

CT-definable subtypes of chronic obstructive pulmonary disease: a statement of the Fleischner Society

DA Lynch, JHM Austin, JC Hogg, PA Grenier… - Radiology, 2015 - pubs.rsna.org
The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

The performance of chest CT in evaluating the clinical severity of COVID-19 pneumonia: identifying critical cases based on CT characteristics

P Lyu, X Liu, R Zhang, L Shi, J Gao - Investigative radiology, 2020 - journals.lww.com
Objectives The aim of this study was to assess the clinical severity of COVID-19 pneumonia
using qualitative and/or quantitative chest computed tomography (CT) indicators and identify …

Computed tomographic measures of pulmonary vascular morphology in smokers and their clinical implications

RSJ Estépar, GL Kinney, JL Black-Shinn… - American journal of …, 2013 - atsjournals.org
Rationale: Angiographic investigation suggests that pulmonary vascular remodeling in
smokers is characterized by distal pruning of the blood vessels. Objectives: Using volumetric …

Idiopathic pulmonary fibrosis: data-driven textural analysis of extent of fibrosis at baseline and 15-month follow-up

SM Humphries, K Yagihashi, J Huckleberry, BH Rho… - Radiology, 2017 - pubs.rsna.org
Purpose To evaluate associations between pulmonary function and both quantitative
analysis and visual assessment of thin-section computed tomography (CT) images at …

[HTML][HTML] Asthma control, airway mucus, and 129Xe MRI ventilation after a single benralizumab dose

MJ McIntosh, HK Kooner, RL Eddy, S Jeimy, C Licskai… - Chest, 2022 - Elsevier
Background Patients with eosinophilic asthma often report poor symptomatic control and
quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes …

Sex differences in airways at chest CT: results from the COPDGene cohort

SP Bhatt, S Bodduluri, A Nakhmani, Y Kim… - Radiology, 2022 - pubs.rsna.org
Background The prevalence of chronic obstructive pulmonary disease (COPD) in women is
fast approaching that in men, and women experience greater symptom burden. Although …

Reduced bone density and vertebral fractures in smokers. Men and COPD patients at increased risk

JD Jaramillo, C Wilson, DJ Stinson… - Annals of the …, 2015 - atsjournals.org
Rationale: Former smoking history and chronic obstructive pulmonary disease (COPD) are
potential risk factors for osteoporosis and fractures. Under existing guidelines for …

Age-related structural and functional changes in the mouse lung

H Schulte, C Mühlfeld, C Brandenberger - Frontiers in physiology, 2019 - frontiersin.org
Lung function declines with advancing age. To improve our understanding of the structure-
function relationships leading to this decline, we investigated structural alterations in the …