Geographic distribution, clinical epidemiology and genetic diversity of the human oncogenic retrovirus HTLV-1 in Africa, the world's largest endemic area

A Gessain, JL Ramassamy, PV Afonso… - Frontiers in …, 2023 - frontiersin.org
The African continent is considered the largest high endemic area for the oncogenic
retrovirus HTLV-1 with an estimated two to five million infected individuals. However, data on …

Molecular epidemiology, genetic variability and evolution of HTLV-1 with special emphasis on African genotypes

PV Afonso, O Cassar, A Gessain - Retrovirology, 2019 - Springer
Human T cell leukemia virus (HTLV-1) is an oncoretrovirus that infects at least 10 million
people worldwide. HTLV-1 exhibits a remarkable genetic stability, however, viral strains …

HTLV in South America: Origins of a silent ancient human infection

R Ishak, MO Guimarães Ishak, VN Azevedo… - Virus …, 2020 - academic.oup.com
The description of the first human retrovirus, human T-lymphotropic virus 1 (HTLV-1), was
soon associated with an aggressive lymphoma and a chronic inflammatory …

HTLV, a multi organ oncovirus

S Ramezani, SA Rezaee, Z Farjami, N Ebrahimi… - Microbial …, 2022 - Elsevier
Human T lymphotropic virus (HTLV-I) is a retrovirus that has been recognized as a causative
agent of two crucidal diseases, HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis …

Seroprevalence of human T‐lymphotropic virus (HTLV) in blood donors in sub‐Saharan Africa: A systematic review and meta‐analysis

AM Ngoma, MD Omokoko, PB Mutombo… - Vox …, 2019 - Wiley Online Library
Background and objective Human T‐cell lymphotropic viruses (HTLV) 1 and 2 are endemic
in sub‐Saharan Africa (SSA), transfusion‐transmissible and causally linked to various …

Diversity of Human T-Lymphotropic Virus Type 1 Cosmopolitan Subtype (HTLV-1a) Circulating in Infected Residents in Portugal

M Quina, D Ramos, C Silva, E Pádua - AIDS Research and Human …, 2024 - liebertpub.com
Human t-cell lymphotropic virus type 1 (HTLV-1) prevalence in Portugal is low and mainly
affects immigrants from endemic areas where human immunodeficiency virus (HIV) infection …

Molecular epidemiology of endemic human T-lymphotropic virus type 1 in a rural community in Guinea-Bissau

C van Tienen, TI de Silva, LCJ Alcantara… - PLoS neglected …, 2012 - journals.plos.org
Background Human T-Lymphotropic Virus Type 1 (HTLV-1) infection causes lethal adult T-
cell leukemia (ATL) and severely debilitating HTLV-associated myelopathy/tropical spastic …

Human T-lymphotropic virus 1aA circulation and risk factors for sexually transmitted infections in an Amazon geographic area with lowest human development index …

SA de Aguiar, SA de Souza França, BB Santana… - BMC Infectious …, 2017 - Springer
Background This cross-sectional study evaluated the prevalence of infection with human T-
lymphotropic virus 1 and 2 (HTLV-1 and HTLV-2) in a population from the municipalities of …

HTLV-1aA introduction into Brazil and its association with the trans-Atlantic slave trade

AER Amoussa, E Wilkinson, M Giovanetti… - Infection, Genetics and …, 2017 - Elsevier
Introduction Human T-lymphotropic virus (HTLV) is an endemic virus in some parts of the
world, with Africa being home to most of the viral genetic diversity. In Brazil, HTLV-1 is …

[HTML][HTML] Prevalence and molecular epidemiology of human T-lymphotropic virus type 1 among women attending antenatal clinics in Sub-Saharan Africa: A systematic …

AM Ngoma, PB Mutombo, MD Omokoko… - The American Journal …, 2019 - ncbi.nlm.nih.gov
Human T-cell lymphotropic virus type 1 (HTLV-1) imposes a substantial disease burden in
sub-Saharan Africa (SSA), which is arguably the world's largest endemic area for HTLV-1 …