The use of immune checkpoint inhibitors (ICIs) has evolved rapidly with unprecedented
treatment benefits being obtained for cancer patients, including improved patient survival …

Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …

The immune system provides full protection for the body by specifically identifying 'self'and
removing 'others'; thus protecting the body from diseases. The immune system includes …

Approximately, 15% of global breast cancer cases are diagnosed as triple-negative breast
cancer (TNBC), identified as the most aggressive subtype due to the simultaneous absence …

Immune checkpoints inhibitors are effective but it needs more precise biomarkers for patient
selection. We explored the biological significance of LINC00862 in pan-cancer by …

Immunotherapies, including immune checkpoint inhibitors, have limitations in their effective
treatment of malignancies. The immunosuppressive environment associated with the tumor …

Camrelizumab, a monoclonal antibody, blocks programmed cell death protein-1 from
binding to T cells and programmed cell death ligand 1 on tumor cells, thereby ensuring …

Simple Summary Cyclooxygenase-2 (COX-2) expression causes several changes in the
tumor microenvironment (TME) of ovarian cancer, which are associated with a low …

Hepatocytes exert pivotal roles in metabolism, protein synthesis and detoxification. Non-
parenchymal liver cells (NPCs), largely comprising macrophages, dendritic cells, hepatic …