Advances in nanomaterial-based electrochemical biosensors for the detection of microbial toxins, pathogenic bacteria in food matrices

R Gupta, N Raza, SK Bhardwaj, K Vikrant… - Journal of hazardous …, 2021 - Elsevier
There is a growing demand to protect food products against the hazard of microbes and their
toxins. To satisfy such goals, it is important to develop highly sensitive, reliable …

Aflatoxin B1: Metabolism, toxicology, and its involvement in oxidative stress and cancer development

W Cao, P Yu, KP Yang, D Cao - Toxicology Mechanisms and …, 2022 - Taylor & Francis
Aflatoxins are a class of carcinogenic mycotoxins produced by Aspergillus fungi, which are
widely distributed in nature. Aflatoxin B1 (AFB1) is the most toxic of these compounds and its …

[HTML][HTML] SeMet attenuates AFB1-induced intestinal injury in rabbits by activating the Nrf2 pathway

Z Zhang, Q Zhang, M Li, J Xu, J Wang, M Li… - Ecotoxicology and …, 2022 - Elsevier
The aim of this study was to investigate the role of selenomethionine (SeMet) in alleviating
AFB1 induced intestinal injury by inhibiting intestinal oxidative stress. Forty 35-day-old …

[HTML][HTML] May phytophenolics alleviate aflatoxins-induced health challenges? A holistic insight on current landscape and future prospects

H Rasouli, FD Nayeri, R Khodarahmi - Frontiers in nutrition, 2022 - frontiersin.org
The emergence of aflatoxins (AFs) raised serious global concerns about world food safety.
AFs are lethal carcinogenic mycotoxins, causing damage to the liver, kidney, and …

Interferon gamma induces inflammatory responses through the interaction of CEACAM1 and PI3K in airway epithelial cells

Y Zhu, D Song, Y Song, X Wang - Journal of translational medicine, 2019 - Springer
Background Interferon gamma (IFNγ) plays an important role in the development of chronic
lung diseases via the production of inflammatory mediators, although the exact mechanism …

Protein arginine methyltransferase 5 (PRMT5) and the ERK1/2 & PI3K pathways: a case for PRMT5 inhibition and combination therapies in cancer

T Sapir, D Shifteh, M Pahmer, S Goel, R Maitra - Molecular Cancer Research, 2021 - AACR
Abstract The ERK1/2 (RAS, RAF, MEK, ERK) and PI3K (PI3K, AKT, mTOR, PTEN) pathways
are the chief signaling pathways for cellular proliferation, survival, and differentiation …

Epigenetic alterations induced by aflatoxin B1: An in vitro and in vivo approach with emphasis on enhancer of zeste homologue-2/p21 axis

P Soni, MS Ghufran, S Olakkaran… - Science of the Total …, 2021 - Elsevier
The potent environmental toxicant aflatoxin B 1 (AFB 1), is a group I carcinogen reported to
induce the expression of many cancer associated proteins. Epigenetic alterations such as …

Clinical significance of P16 gene methylation in lung cancer

Y Li, T Zhang, H Zhang, X Wang, X Liu… - Single-cell Sequencing …, 2020 - Springer
Lung cancer is the leading cause of death from cancer in China. The lack of early screening
technologies makes most patients to be diagnosed at advanced stages with a poor …

Development of portable and reusable optical fiber chemiluminescence biosensing platform for rapid on-site detection of Aflatoxin B1

Z Yi, Y Ren, Y Li, F Long, A Zhu - Microchemical Journal, 2023 - Elsevier
A portable and reusable optical fiber chemiluminescence biosensing platform (OFCBP) was
constructed for rapid and on-site detection of Aflatoxin B1 (AFB1) using optical fiber as …

The global concern for cancer emergence and its prevention: a systematic unveiling of the present scenario

MS Ghufran, P Soni, GR Duddukuri - Bioprospecting of Tropical Medicinal …, 2023 - Springer
Cancer is a deadly disease and ranks as the second leading cause of death globally, which
predominantly arises as a result of continuous exposure of human beings to carcinogenic …