[HTML][HTML] The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases

L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Thromboinflammation in COVID-19 acute lung injury

WB Mitchell - Paediatric respiratory reviews, 2020 - Elsevier
Since the initial description in 2019, the novel coronavirus SARS-Cov-2 infection (COVID-
19) pandemic has swept the globe. The most severe form of the disease presents with fever …

Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 …

APJ Vlaar, S de Bruin, M Busch… - The Lancet …, 2020 - thelancet.com
Background Severe COVID-19 is characterised by inflammation and coagulation in the
presence of complement system activation. We aimed to explore the potential benefit and …

[HTML][HTML] Thrombo-inflammation in cardiovascular disease: an expert consensus document from the Third Maastricht Consensus Conference on Thrombosis

E d'Alessandro, C Becker, W Bergmeier… - Thrombosis and …, 2020 - thieme-connect.com
Thrombo-inflammation describes the complex interplay between blood coagulation and
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …

[HTML][HTML] The role of monocytes in thrombotic diseases: A review

Z Han, Q Liu, H Li, M Zhang, L You, Y Lin… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular and cerebrovascular diseases are the number one killer threatening
people's life and health, among which cardiovascular thrombotic events are the most …

Chronic thromboembolic pulmonary hypertension: realising the potential of multimodal management

M Delcroix, M de Perrot, X Jaïs, DP Jenkins… - The Lancet …, 2023 - thelancet.com
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute
pulmonary embolism. Important advances have enabled better understanding …

[HTML][HTML] Biosensor and Lab-on-a-chip Biomarker-identifying Technologies for Oral and Periodontal Diseases

L Steigmann, S Maekawa, C Sima, S Travan… - Frontiers in …, 2020 - frontiersin.org
Periodontitis is a complex multifactorial disease that can lead to destruction of tooth
supporting tissues and subsequent tooth loss. The most recent global burden of disease …

[HTML][HTML] Neutrophil extracellular traps mediate deep vein thrombosis: From mechanism to therapy

M Yao, J Ma, D Wu, C Fang, Z Wang, T Guo… - Frontiers in …, 2023 - frontiersin.org
Deep venous thrombosis (DVT) is a part of venous thromboembolism (VTE) that clinically
manifests as swelling and pain in the lower limbs. The most serious clinical complication of …

[HTML][HTML] Thrombolytic enzymes of microbial origin: a review

D Diwan, Z Usmani, M Sharma, JW Nelson… - International journal of …, 2021 - mdpi.com
Enzyme therapies are attracting significant attention as thrombolytic drugs during the current
scenario owing to their great affinity, specificity, catalytic activity, and stability. Among various …

Bromelain: A review of its mechanisms, pharmacological effects and potential applications

V Kumar, B Mangla, S Javed, W Ahsan, P Kumar… - Food & Function, 2023 - pubs.rsc.org
The utilization of plant-derived supplements for disease prevention and treatment has long
been recognized because of their remarkable potential. Ananas comosus, commonly known …