Mechanics of membrane fusion

LV Chernomordik, MM Kozlov - Nature structural & molecular biology, 2008 - nature.com
Diverse membrane fusion reactions in biology involve close contact between two lipid
bilayers, followed by the local distortion of the individual bilayers and reformation into a …

[HTML][HTML] Membrane hemifusion: crossing a chasm in two leaps

LV Chernomordik, MM Kozlov - Cell, 2005 - cell.com
During membrane fusion, the outer leaflets of the two membranes merge first, whereas the
distal membrane leaflets remain separate until the opening of a fusion pore. This …

Adsorption of divalent cations to bilayer membranes containing phosphatidylserine.

S McLAUGHLIN, N Mulrine, T Gresalfi, G Vaio… - The Journal of general …, 1981 - rupress.org
The Stern equation, a combination of the Langmuir adsorption isotherm, the Boltzmann
relation, and the Grahame equation from the theory of the diffuse double layer, provides a …

[PDF][PDF] The hemifusion intermediate and its conversion to complete fusion: regulation by membrane composition

L Chernomordik, A Chanturiya, J Green… - Biophysical journal, 1995 - cell.com
To fuse, membranes must bend. The energy of each lipid monolayer with respect to bending
is minimized at the spontaneous curvature of the monolayer. Two lipids known to promote …

Reconstitution in planar lipid bilayers of a Ca2+-dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle.

R Latorre, C Vergara, C Hidalgo - Proceedings of the …, 1982 - National Acad Sciences
Addition of membrane vesicles prepared from transverse tubule (T-tubule) membranes of
rabbit skeletal muscle to the aqueous phase of a planar lipid bilayer induces a stepwise …

Molecular mechanisms and forces involved in the adhesion and fusion of amphiphilic bilayers

CA Helm, JN Israelachvili, PM McGuiggan - science, 1989 - science.org
The surface forces apparatus technique was used for measuring the adhesion, deformation,
and fusion of bilayers supported on mica surfaces in aqueous solutions. The most important …

Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel

J Zimmerberg, VA Parsegian - Nature, 1986 - nature.com
Osmotic stress can be used to estimate the internal volume change during the opening and
closing of a voltage gated ionic channel. Mitochondrial voltage-dependent anion channels …

[HTML][HTML] Membranes of the world unite!

LV Chernomordik, J Zimmerberg… - The Journal of cell …, 2006 - ncbi.nlm.nih.gov
Despite diverse origins, cellular fusion mechanisms converge at a pathway of phospholipid
bilayer fusion. In this mini-review, we discuss how proteins can mediate each of the three …

[PDF][PDF] Phospholipid bilayers made from monolayers on patch-clamp pipettes

R Coronado, R Latorre - Biophysical journal, 1983 - cell.com
Phospholipid bilayers were made from phospholipid monolayers at the air/water interface on
patch-clamp pipettes. Lipid bilayers were characterized using the K+ carrier nonactin and …

Flickering fusion pores comparable with initial exocytotic pores occur in protein-free phospholipid bilayers

A Chanturiya, LV Chernomordik… - Proceedings of the …, 1997 - National Acad Sciences
For the act of membrane fusion, there are two competing, mutually exclusive molecular
models that differ in the structure of the initial pore, the pathway for ionic continuity between …