Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …

Inhalation of silica particles is an environmental and occupational cause of silicosis, a type
of pneumoconiosis. Development of the lung silicosis is a unique process in which the …

The concept of the inflammasome, a macromolecular complex sensing cell stress or danger
signals and initiating inflammation, was first introduced approximately a decade ago …

Post-breeding endometritis (ie, inflammation/infection of the endometrium), is a
physiological reaction taking place in the endometrium of mares within 48 h post-breeding …

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2), a member of the
NOD-like receptors family, are crucial for innate immune responses. Mutations of NOD2 …

Background NOD-like receptors affect multiple stages of cancer progression in many
malignancies. NACHT, LRR, and PYD domain-containing protein 7 (NLRP7) is a member of …

Non-self recognition with the consequent tolerance or immune reaction is a crucial process
to succeed as living organisms. At the same time the interactions between host species and …

Severe asthma (SA) is a chronic lung disease characterized by recurring symptoms of
reversible airflow obstruction, airway hyper-responsiveness (AHR), and inflammation that is …

Background The Nod-like receptor NACHT, LRR, and PYD domain–containing protein 3
(NLRP3) and Bruton tyrosine kinase (BTK) are protagonists in innate and adaptive immunity …

Biomaterial implants are an established part of medical practice, encompassing a broad
range of devices that widely differ in function and structural composition. However, one …