Targetable Conformationally Restricted Cyanines Enable Photon‐Count‐Limited Applications

P Eiring, R McLaughlin, SS Matikonda… - Angewandte Chemie …, 2021 - Wiley Online Library
Cyanine dyes are exceptionally useful probes for a range of fluorescence‐based
applications, but their photon output can be limited by trans‐to‐cis photoisomerization. We …

Synthesis of Heptamethine Cyanines from Furfural Derivatives

Z Hao, L Hu, X Wang, Y Liu, S Mo - Organic Letters, 2023 - ACS Publications
Despite the widespread theranostic utilization of cyanine dyes (Cy7), their synthetic method
is still limited with pyridine or cyclohexanone derivatives as starting materials. Herein, we …

A general strategy to develop fluorogenic polymethine dyes for bioimaging

A Martin, P Rivera-Fuentes - Nature Chemistry, 2024 - nature.com
Fluorescence imaging is an invaluable tool to study biological processes and further
progress depends on the development of advanced fluorogenic probes that reach …

SiaNAl can be efficiently incorporated in glycoproteins of human mesenchymal stromal cells by metabolic glycoengineering

J Mut, S Altmann, S Reising… - ACS Biomaterials …, 2023 - ACS Publications
Metabolic glycoengineering involves the stimulation of cells with functionalized
monosaccharides. Glucosamine, galactosamine, and mannosamine derivatives are …

Synthesis of polyethylene-based covalent adaptable networks including 1, 2, 3-triazolium or imine dynamic cross-links by reactive processing

B Rigatelli, D Montarnal, E Drockenmuller - Polymer, 2024 - Elsevier
Polyethylene-based covalent adaptable networks (PE CANs) are obtained by reactive
extrusion in a micro-compounder of a commercial maleic anhydride-grafted polyethylene …

Metabolic glycoengineering in hMSC-TERT as a model for skeletal precursors by using modified azide/alkyne monosaccharides

S Altmann, J Mut, N Wolf, J Meißner-Weigl… - International Journal of …, 2021 - mdpi.com
Metabolic glycoengineering enables a directed modification of cell surfaces by introducing
target molecules to surface proteins displaying new features. Biochemical pathways …

A Modular Approach for the Synthesis of Diverse Heterobifunctional Cyanine Dyes

C Maller, F Schedel, M Köhn - The Journal of Organic Chemistry, 2024 - ACS Publications
Herein, we present a straightforward synthetic route for the design and synthesis of diverse
heterobifunctional cyanine 5 dyes. We optimized the workup by harnessing the pH-and …

Synthesis and characterization of a water-soluble pentamethine indocyanine dye for peptide labeling

CDF Martins, MMM Raposo, SPG Costa - Chemistry Proceedings, 2022 - mdpi.com
A water-soluble pentamethine cyanine dye was synthesized for further conjugation with
peptides. The dye preparation was accomplished by solution-phase chemistry and the …

Novel hemicyanine dyes with a large Stokes shift and strong fluorescence: mitochondrial-targeted imaging

CQ Li, ZH Sun, KJ Bian, QG Zhang, LW Zou - Chemical Papers, 2024 - Springer
Hemicyanine dyes have a donor-π-acceptor (D-π-A) system that offers potential applications
in mitochondrial-targeted analysis. However, there are currently few hemicyanide dyes with …

A sulfo-cyanine dye as a colorimetric chemosensor for metal cation recognition

CDF Martins, MMM Raposo, SPG Costa - Engineering Proceedings, 2022 - mdpi.com
Metal cations play important roles in several industrial and biochemical processes.
However, high levels of some cations are toxic and consequently cause serious health and …