[HTML][HTML] Potential Underlying Mechanisms Explaining the Cardiorenal Benefits of Sodium–Glucose Cotransporter 2 Inhibitors

S Verma, S Mudaliar, PJ Greasley - Advances in Therapy, 2024 - Springer
There is a bidirectional pathophysiological interaction between the heart and the kidneys,
and prolonged physiological stress to the heart and/or the kidneys can cause adverse …

[HTML][HTML] Epicardial adipose tissue is associated with left atrial volume and fibrosis in patients with atrial fibrillation

Y Chahine, B Askari-Atapour, KT Kwan… - Frontiers in …, 2022 - frontiersin.org
Background Obesity is a risk factor for atrial fibrillation (AF) and strongly influences the
response to treatment. Atrial fibrosis shows similar associations. Epicardial adipose tissue …

[HTML][HTML] Putative protective effects of sodium-glucose cotransporter 2 inhibitors on atrial fibrillation through risk factor modulation and off-target actions: potential …

SS Shetty, A Krumerman - Cardiovascular diabetology, 2022 - Springer
Atrial fibrillation, the most common cardiac arrhythmia, results in substantial morbidity and
mortality related to its increased risks of stroke, heart failure, and impaired cognitive function …

[HTML][HTML] Relationships between epicardial adipose tissue thickness and adipo-fibrokine indicator profiles post-myocardial infarction

O Gruzdeva, E Uchasova, Y Dyleva… - Cardiovascular …, 2018 - Springer
Background Determination of the impact of visceral obesity and epicardial adipose tissue
thickness on stimulating growth factor levels during hospitalization for myocardial infarction …

[HTML][HTML] Epicardial adipose tissue and postoperative atrial fibrillation

L Petraglia, M Conte, G Comentale… - Frontiers in …, 2022 - frontiersin.org
Background Atrial fibrillation (AF) often occurs after cardiac surgery and is associated with
increased risk of stroke and mortality. Prior studies support the important role of inflammation …

WNT signaling in atrial fibrillation

C Wolke, E Antileo… - Experimental Biology and …, 2021 - journals.sagepub.com
The Wnt signaling pathway regulates physiological processes such as cell proliferation and
differentiation, cell fate decisions, and stem cell maintenance and, thus, plays essential roles …

Impact of the cardiovascular system-associated adipose tissue on atherosclerotic pathology

DA Chistiakov, AV Grechko, VA Myasoedova… - Atherosclerosis, 2017 - Elsevier
Cardiac obesity makes an important contribution to the pathogenesis of cardiovascular
disease. One of the important pathways of this contribution is the inflammatory process that …

[HTML][HTML] Genome-wide screening of functional long noncoding RNAs in the epicardial adipose tissues of atrial fibrillation

X Shi, X Shao, B Liu, M Lv, P Pandey, C Guo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Atrial fibrillation (AF) is the most common arrhythmias, and patients with AF are facing
increased risk of heart failure and ischemic stroke. However, the AF pathogenesis …

GLP‐1 analogs and regional adiposity: A systematic review and meta‐analysis

I Akoumianakis, A Zagaliotis, M Konstantaraki… - Obesity …, 2023 - Wiley Online Library
Background Glucagon‐like peptide 1 (GLP‐1) analogs regulate body weight and liver
steatosis. Different body adipose tissue (AT) depots exhibit biological variability …

[HTML][HTML] Mechanotransduction regulates inflammation responses of epicardial adipocytes in cardiovascular diseases

X Liu, L Liu, J Zhao, H Wang, Y Li - Frontiers in endocrinology, 2022 - frontiersin.org
Adipose tissue is a crucial regulator in maintaining cardiovascular homeostasis by secreting
various bioactive products to mediate the physiological function of the cardiovascular …