Immune cell recruitment and migration is central to the normal functioning of the immune
system in health and disease. Numerous adhesion molecules on immune cells and the …

Gastric cancer is the fourth and fifth most common cancer worldwide in men and women,
respectively. However, patients with an advanced stage of gastric cancer still have a poor …

Correct classification of cancer patients into subtypes is a prerequisite for acute diagnosis
and effective treatment. Currently this classification relies mainly on histological assessment …

The introduction of chimeric antigen receptor (CAR)‐modified T cells has revolutionized
immunotherapy and cancer treatment as a whole. However, so far, clinical efficacy has only …

The presence of CD19 in myelomatous plasma cells (MM-PCs) correlates with adverse
prognosis in multiple myeloma (MM). Although CD19 expression is upregulated by CD81 …

Worldwide, B cell non-Hodgkin lymphoma is the most common hematological malignancy
and represents a substantial clinical problem. The molecular events that lead to B cell …

CD81 participates in a variety of important cellular processes such as membrane
organization, protein trafficking, cellular fusion and cell–cell interactions. In the immune …

The tetraspanin CD81 was initially discovered by screening mAbs elicited against a human
B cell lymphoma for their direct antiproliferative effects. We now show that 5A6, one of the …

Highlights•Tetraspanins are small membrane proteins with major role in cell signaling.•
Tetraspanins are important actors in proliferative, immunologic and infectious pathological …

CD81, a member of the tetraspanin family, has been revealed to be upregulated and
associated with prognosis in several types of cancer; however, this relationship has not …