Objective: We reviewed evidence regarding a possible relationship between mood
disorders and obesity to better inform mental health professionals about their overlap …

A majority of psychiatric medications are known to generate weight gain and ultimately
obesity in some patients. There is much speculation about the prevalence of weight gain …

Background Topiramate is a new antiepileptic drug, originally designed as an oral
hypoglycaemic subsequently approved as anticonvulsant. It has increasingly been used in …

Increasing evidence suggests that abnormalities in amino neurotransmission are associated
with the neurobiology of depression. Preclinical studies demonstrate that GABA modulating …

Borderline personality disorder is a common and severe psychiatric illness. The goal of this
study was to determine whether topiramate can influence patients' borderline …

Major depressive disorder (MDD) is highly prevalent, potentially disabling, and sometimes
fatal. Antidepressants (ADs) have improved its treatment, but incomplete response …

Background: The aim of this study was to test the efficacy and safety of olanzapine+
topiramate versus olanzapine monotherapy in the treatment of bipolar disorder (BPD) and …

BACKGROUND: Depression is associated with increased aggression and diminished ability
and quality of life. The goal of this study was to compare the efficacy of topiramate in …

Background Bipolar disorder is a common recurrent illness with high levels of chronicity.
Previous trials have suggested that the anticonvulsant topiramate may be efficacious in …

BACKGROUND: Despite evolution of new antidepressant treatment, clinicians still
encounter challenges in the treatment of depressed patients. Looking for new medications …