The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

R Bai, Y Li, L Jian, Y Yang, L Zhao, M Wei - Molecular Cancer, 2022 - Springer
Given that hypoxia is a persistent physiological feature of many different solid tumors and a
key driver for cancer malignancy, it is thought to be a major target in cancer treatment …

Exosomes: A potential tool for immunotherapy of ovarian cancer

X Gong, H Chi, DF Strohmer, AT Teichmann… - Frontiers in …, 2023 - frontiersin.org
Ovarian cancer is a malignant tumor of the female reproductive system, with a very poor
prognosis and high mortality rates. Chemotherapy and radiotherapy are the most common …

Combined single‐cell and spatial transcriptomics reveal the metabolic evolvement of breast cancer during early dissemination

YM Liu, JY Ge, YF Chen, T Liu, L Chen… - Advanced …, 2023 - Wiley Online Library
Breast cancer is now the most frequently diagnosed malignancy, and metastasis remains
the leading cause of death in breast cancer. However, little is known about the dynamic …

The role of extracellular vesicles in circulating tumor cell-mediated distant metastasis

S Guo, J Huang, G Li, W Chen, Z Li, J Lei - Molecular Cancer, 2023 - Springer
Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor
cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary …

The variety of 3D breast cancer models for the study of tumor physiology and drug screening

E Fröhlich - International Journal of Molecular Sciences, 2023 - mdpi.com
Breast cancer is the most common cancer in women and responsible for multiple deaths
worldwide. 3D cancer models enable a better representation of tumor physiology than the …

Angiogenesis in lung cancer: understanding the roles of growth factors

TYS Ngaha, AV Zhilenkova, FE Essogmo, IK Uchendu… - Cancers, 2023 - mdpi.com
Simple Summary Growth factors promote angiogenesis, which is a critical process in the
development of tumors. One of the therapeutic techniques being investigated in the …

Extracellular vesicles in breast cancer: from biology and function to clinical diagnosis and therapeutic management

S Loric, JA Denis, C Desbene, M Sabbah… - International journal of …, 2023 - mdpi.com
Breast cancer (BC) is the first worldwide most frequent cancer in both sexes and the most
commonly diagnosed in females. Although BC mortality has been thoroughly declining over …

Onco-Breastomics: An Eco-Evo-Devo Holistic Approach

AN Neagu, D Whitham, P Bruno, A Arshad… - International Journal of …, 2024 - mdpi.com
Known as a diverse collection of neoplastic diseases, breast cancer (BC) can be
hyperbolically characterized as a dynamic pseudo-organ, a living organism able to build a …

The binomial “inflammation-epigenetics” in breast cancer progression and bone metastasis: IL-1β actions are influenced by TET inhibitor in MCF-7 cell line

D Bellavia, V Costa, A De Luca, A Cordaro… - International Journal of …, 2022 - mdpi.com
The existence of a tight relationship between inflammation and epigenetics that in primary
breast tumor cells can lead to tumor progression and the formation of bone metastases was …

Manganese-mineralized cancer cells as immunogenic cancer vaccines for tumor immunotherapy

Z Liu, J Lin, B Li, Y Zhou, C Li, Y Cui, F Tian… - Journal of Materials …, 2023 - pubs.rsc.org
The strategy of using tumor cells to construct whole-cell cancer vaccines has received
widespread attention. However, the limited immunogenicity of inactivated tumor cells and …