Management of REM sleep behavior disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment

M Howell, AY Avidan, N Foldvary-Schaefer… - Journal of Clinical …, 2023 - jcsm.aasm.org
This systematic review provides supporting evidence for a clinical practice guideline for the
management of rapid eye movement (REM) sleep behavior disorder in adults and children …

Glymphatic system dysfunction and sleep disturbance may contribute to the pathogenesis and progression of Parkinson's disease

A Massey, MK Boag, A Magnier, DPCF Bispo… - International journal of …, 2022 - mdpi.com
Parkinson's disease (PD) is a multisystem alpha-synucleinopathic neurodegenerative
disease and the most prevalent neurodegenerative disorder after Alzheimer's disease with a …

Non-motor outcomes depend on location of neurostimulation in Parkinson's disease

JN Petry-Schmelzer, M Krause, TA Dembek, A Horn… - Brain, 2019 - academic.oup.com
Deep brain stimulation of the subthalamic nucleus is an effective and established therapy for
patients with advanced Parkinson's disease improving quality of life, motor symptoms and …

[HTML][HTML] Adaptive Deep Brain Stimulation for sleep stage targeting in Parkinson's disease

C Smyth, MF Anjum, S Ravi, T Denison, P Starr, S Little - Brain stimulation, 2023 - Elsevier
Background Sleep dysfunction is disabling in people with Parkinson's disease and is linked
to worse motor and non-motor outcomes. Sleep-specific adaptive Deep Brain Stimulation …

Diurnal modulation of subthalamic beta oscillatory power in Parkinson's disease patients during deep brain stimulation

JJ van Rheede, LK Feldmann, JL Busch… - npj Parkinson's …, 2022 - nature.com
Beta-band activity in the subthalamic local field potential (LFP) is correlated with Parkinson's
disease (PD) symptom severity and is the therapeutic target of deep brain stimulation (DBS) …

The neurophysiology of sleep in Parkinson's disease

H Zahed, JRP Zuzuarregui, R Gilron… - Movement …, 2021 - Wiley Online Library
Sleep disturbances are among the most common nonmotor complications of Parkinson's
disease (PD), can present in prodromal stages, and progress with advancing disease. In …

Slow‐wave sleep and motor progression in Parkinson disease

SJ Schreiner, LL Imbach, E Werth… - Annals of …, 2019 - Wiley Online Library
Growing evidence from Alzheimer disease supports a potentially beneficial role of slow‐
wave sleep in neurodegeneration. However, the importance of slow‐wave sleep in …

An overview of sleep and circadian dysfunction in Parkinson's disease

S Mantovani, SS Smith, R Gordon… - Journal of Sleep …, 2018 - Wiley Online Library
Sleep and circadian alterations are amongst the very first symptoms experienced in
Parkinson's disease, and sleep alterations are present in the majority of patients with overt …

[HTML][HTML] Etiologies of insomnia in Parkinson's disease–Lessons from human studies and animal models

AD Mizrahi-Kliger, LK Feldmann, AA Kühn… - Experimental …, 2022 - Elsevier
Sleep disorders are integral to Parkinson's disease (PD). Insomnia, an inability to maintain
stable sleep, affects most patients and is widely rated as one of the most debilitating facets of …

Sodium oxybate for excessive daytime sleepiness and sleep disturbance in Parkinson disease: a randomized clinical trial

F Büchele, M Hackius, SR Schreglmann… - JAMA …, 2018 - jamanetwork.com
Importance Sleep-wake disorders are a common and debilitating nonmotor manifestation of
Parkinson disease (PD), but treatment options are scarce. Objective To determine whether …