Acquired immunity to malaria

DL Doolan, C Dobaño, JK Baird - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Naturally acquired immunity to falciparum malaria protects millions of people routinely
exposed to Plasmodium falciparum infection from severe disease and death. There is no …

Antigenic Variation in Plasmodium falciparum

A Scherf, JJ Lopez-Rubio, L Riviere - Annu. Rev. Microbiol., 2008 - annualreviews.org
The persistence of the human malaria parasite Plasmodium falciparum during blood stage
proliferation in its host depends on the successive expression of variant molecules at the …

Sequestration and tissue accumulation of human malaria parasites: can we learn anything from rodent models of malaria?

B Franke-Fayard, J Fonager, A Braks, SM Khan… - PLoS …, 2010 - journals.plos.org
The sequestration of Plasmodium falciparum–infected red blood cells (irbcs) in the
microvasculature of organs is associated with severe disease; correspondingly, the …

Antigenic Variation in Plasmodium falciparum: Gene Organization and Regulation of the var Multigene Family

SA Kyes, SM Kraemer, JD Smith - Eukaryotic cell, 2007 - Am Soc Microbiol
Plasmodium falciparum imposes an enormous burden upon the developing world, with 300
to 500 million cases and 1 to 2 million deaths per year (94). Despite extensive research …

[HTML][HTML] Harnessing the potential of miRNAs in malaria diagnostic and prevention

H Gupta, SC Wassmer - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Despite encouraging progress over the past decade, malaria remains a major global health
challenge. Severe malaria accounts for the majority of malaria-related deaths, and early …

Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A

K Singh, AG Gittis, P Nguyen, DC Gowda… - Nature structural & …, 2008 - nature.com
Plasmodium falciparum–infected erythrocytes bind to chondroitin sulfate A (CSA) in the
placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane …

Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA

P Andersen, MA Nielsen, M Resende, TS Rask… - PLoS …, 2008 - journals.plos.org
Pregnancy-associated malaria is caused by Plasmodium falciparum malaria parasites
binding specifically to chondroitin sulfate A in the placenta. This sequestration of parasites is …

Submicroscopic infection of placenta by Plasmodium produces Th1/Th2 cytokine imbalance, inflammation and hypoxia in women from north-west Colombia

OM Agudelo, BH Aristizabal, SK Yanow, E Arango… - Malaria journal, 2014 - Springer
Background A large-scale study was set up in order to study the epidemiology, clinical
aspects, and immunopathology of gestational and placental malaria in north-west Colombia …

Ape parasite origins of human malaria virulence genes

DB Larremore, SA Sundararaman, W Liu… - Nature …, 2015 - nature.com
Antigens encoded by the var gene family are major virulence factors of the human malaria
parasite Plasmodium falciparum, exhibiting enormous intra-and interstrain diversity. Here …

Infection and invasion mechanisms of Trypanosoma cruzi in the congenital transmission of Chagas' disease: a proposal

U Kemmerling, C Bosco, N Galanti - Biological Research, 2010 - SciELO Chile
Chagas' disease is produced by the haemophlagelated protozoan Trypanosoma cruzi and
transmitted by haematophages insects such as Triatoma infestans (vinchuca). Due to vector …