Mechanical ventilation applies physical stresses to the tissues of the lung and thus may give
rise to ventilator-induced lung injury (VILI), particular in patients with acute respiratory …

The charge of this Joint ATS/ERS Task Force was to critically review the state-of-the-art
stereological methods in lung morphometry, provide practical guidelines for use of these …

Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …

The alveolar epithelium consists of squamous alveolar type (AT) I and cuboidal ATII cells.
ATI cells cover 95–98% of the alveolar surface, thereby playing a critical role in barrier …

The American Thoracic Society and the European Society of Intensive Care Medicine
sponsored a meeting of leading investigators in 1992 to discuss key issues about ARDS. A …

Understanding how the mechanisms of ventilator-induced lung injury (VILI), namely
atelectrauma and volutrauma, contribute to the failure of the blood-gas barrier and …

The clinical course of patients with the acute respiratory distress syndrome (ARDS) is quite
variable. One of the most fascinating aspects of this syndrome is that patients with severe …

Although recent X-ray computed tomography (CT) data show that ventral-dorsal gradients in
density are common in the adult respiratory distress syndrome (ARDS), we hypothesized …

The detailed investigation of regional differences in lung function at a local level began
when suitable gamma-ray emitting isotopes and focused external radiation detectors …

In many ways, the lung is an ideal organ for study with positron emission tomography (PET).
First, structure-function relations are homogeneous over larger areas than in other organs …