Chronic rhinosinusitis (CRS) is a multifactorial inflammatory disease of the nose and sinuses
that affects more than 10% of the adult population worldwide. Currently, CRS is classified …

The pathophysiology of CRS is multifactorial and complex yet needs to be completed.
Recent evidence emphasizes the crucial part played by epithelial cells in the development …

To utilize metabolomics in conjunction with RNA sequencing to identify biomarkers in the
blood of sepsis patients and discover novel targets for diagnosing and treating sepsis. In …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by high
tissue heterogeneity and risk of postoperative recurrence, but the underlying mechanisms …

Tumor budding is a long-established independent adverse prognostic marker for colorectal
cancer (CRC), yet assessment of tumor budding was not reproducible. Therefore …

Chronic rhinosinusitis (CRS) represents a heterogeneous disorder primarily characterized
by the persistent inflammation of the nasal cavity and paranasal sinuses. The subtype …

Lipopolysaccharide (LPS) is known to elicit a robust immune response. This study aimed to
investigate the impact of LPS on the transcriptome of human nasal epithelial cells (HNEpC) …

Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an immunologic disease,
and pyroptosis, an inflammation-based cellular death, strictly modulates CRSwNP …

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) presents a high rate of
postoperative recurrence, but its recurrent mechanisms are not fully clarified. In this study …

Elderly patients infected with severe acute respiratory syndrome coronavirus 2 are at higher
risk of severe clinical manifestation, extended hospitalization, and increased mortality …